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Table 2 Adverse reactions based on age and CIRS score

From: Real world risk of infusion reactions and effectiveness of front-line obinutuzumab plus chlorambucil compared with other frontline treatments for chronic lymphocytic leukemia

Toxicity

Total

Age at Treatment

CIRS

75 + 

Under 75

P-valuea

8 + 

Under 8

P-valuea

Infusion-related reaction

29 (43.28)

14 (48.28)

15 (39.47)

0.47

14 (37.84)

15 (50.00)

0.32

Neutropenia

41 (61.19)

18 (62.07)

23 (60.53)

0.90

24 (64.86)

17 (56.67)

0.49

Anemia

25 (37.31)

14 (48.28)

11 (28.95)

0.11

15 (40.54)

10 (33.33)

0.54

Thrombocytopenia

42 (62.69)

19 (65.52)

23 (60.53)

0.68

20 (54.05)

22 (73.33)

0.10

Infections

28 (41.79)

10 (34.48)

18 (47.37)

0.29

16 (43.24)

12 (40.00)

0.79

  1. a Chi-square P-value