Table 6 Univariate and multivariate analyses for overall survival and disease-free survival of the 29 rectal patients with pathological LPNM

Gender: male/female

0.72 (0.19–2.71)

0.99 (0.37–2.71)

Age

1.01 (0.95–1.06)

0.99 (0.96–1.03)

Preoperative treatment

2.73 (0.56–13.34)

1.78 (0.65–4.94)

Preoperative CEA level

0.99 (0.93–1.05)

1.01 (1.00–1.02)

Preoperative CA19-9 level

1.00 (0.99–1.01)

1.00 (0.99–1.01)

Histology

0.89 (0.22–3.64)

1.00 (0.36–2.78)

Perineural invasion

3.89 (0.34–18.10)

2.03 (0.70–5.90)

Vascular invasion

1.06 (0.28–3.99)

0.77 (0.28–2.14)

Lymphatic invasion

6.64 (1.35–32.78)

2.74 (0.44–17.15)

3.03 (1.01–9.10)

1.65 (0.45–5.99)

T stage: T3-4/T1-2

1.17 (0.15–9.42)

0.50 (0.14–1.80)

 N stage

  N0

Reference

Reference

  N1

0.17 (0.15–1.85)

0.62 (0.15–2.63)

  N2

1.83(0.35–9.68)

1.38 (0.34–5.57)

Mesorectal LN harvested

0.98 (0.91–1.06)

1.00 (0.94–1.06)

LPN harvested

1.01 (0.95–1.08)

0.98 (0.92–1.05)

Adjuvant chemotherapy

0.69 (0.17–2.77)

0.39 (0.14–1.08)

Anastomosis leakage or SSI

1.72 (0.26–11.53)

1.42 (0.45–3.93)

High risk LPNM

15.33 (1.77–133.46)

9.23 ( 1.46–87.35)

4.46 (1.38–14.46)

4.39 (1.33–13.16)