Table 5 Odds ratio for metabolic syndrome at follow up, unadjusted and adjusted for age, smoking status and active cancer, in survivors of testicular cancer and childhood cancer (n = 69)
Inflammatory cytokine | Metabolic syndrome | OR (CI) Unadjusted | OR (CI) Adjusteda | |||
|---|---|---|---|---|---|---|
Absent n = 54 (78%) | Present n = 15 (22%) | |||||
IL-6 | ||||||
 Low | 35 | (85) | 6 | (15) | ref. | ref. |
 High | 19 | (68) | 9 | (32) | 2.76 (0.85–8.94) | 1.76 (0.45–6.88) |
IL-8 | ||||||
 Low | 17 | (74) | 6 | (26) | ref. | ref. |
 High | 37 | (80) | 9 | (20) | 0.69 (0.21–2.25) | 0.57 (0.14–2.29) |
TNF-α | ||||||
 Low | 36 | (84) | 7 | (16) | ref. | ref. |
 High | 18 | (69) | 8 | (31) | 2.29 (0.72–7.30) | 4.12 (0.94–18.12) |
IL-10 | ||||||
 Low | 32 | (73) | 12 | (27) | ref. | ref. |
 High | 22 | (88) | 3 | (12) | 0.36 (0.09–1.44) | 0.23 (0.04–1.22) |
IL-6 and IL-10 | ||||||
 Others | 46 | (84) | 9 | (16) | ref. | ref. |
 IL-6 High + IL-10 Low | 8 | (57) | 6 | (43) | 3.83 (1.07–13.75) | 2.71 (0.60–12.38) |