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Table 4 Metabolic risk factors in relation to unadjusted levels of inflammatory cytokines in survivors of testicular cancer and childhood cancer at follow up (n = 71)

From: Low-grade inflammation in survivors of childhood cancer and testicular cancer and its association with hypogonadism and metabolic risk factors

Metabolic parameters

IL-6

IL-8

TNF-α

IL-10

 

Low

High

p

Low

High

p

Low

High

p

Low

High

p

BMI

25.4

(2.6)

28.0

(5.3)

0.017

25.6

(3.0)

27.0

(4.5)

0.181

25.8

(3.3)

27.7

(5.1)

0.061

26.2

(4.3)

27.0

(3.8)

0.415

Waist circumference

90.5

(8.2)

98.9

(14.3)

0.006

91.7

(9.5)

95.2

(12.8)

0.245

92.1

(10.4)

97.1

(13.6)

0.084

93.0

(12.0)

95.7

(11.6)

0.362

Cholesterole

5.1

(0.9)

5.3

(0.9)

0.274

5.4

(1.2)

5.1

(0.8)

0.288

5.1

(0.9)

5.3

(1.0)

0.496

5.2

(1.0)

5.1

(0.9)

0.898

HDL

1.2

(0.2)

1.2

(0.4)

0.542

1.2

(0.4)

1.2

(0.3)

0.631

1.2

(0.3)

1.1

(0.3)

0.330

1.2

(0.3)

1.2

(0.3)

0.372

LDL

3.3

(0.8)

3.5

(0.9)

0.348

3.5

(1.1)

3.4

(0.7)

0.544

3.4

(0.8)

3.5

(0.9)

0.472

3.4

(0.8)

3.5

(0.8)

0.480

Triglycerides

0.8

(0.2–5.2)

0.9

(0.3–3.8)

0.266

1.0

(0.2–5.2)

0.8

(0.3–3.8)

0.522

0.8

(0.2–5.2)

1.1

(0.4–3.8)

0.132

1.0

(0.2–5.2)

0.8

(0.3–2.0)

0.070

Hemoglobin

149.5

(9.3)

148.7

(7.0)

0.706

147.7

(10.1)

149.9

(7.4)

0.313

147.9

(8.2)

151.1

(8.6)

0.131

148.4

(9.1)

150.5

(7.0)

0.347

Insulin

5.0

(2.0–22.0)

7.0

(1.0–25.0)

0.049

5.0

(2.1–22.0)

5.0

(1.0–25.0)

0.368

5.0

(2.0–22.0)

5.5

(1.0–25.0)

0.351

5.0

(1.0–25.0)

6.0

(2.0–22.5)

0.220

Glucose

5.2

(0.5)

5.3

(0.5)

0.441

5.3

(0.5)

5.2

(0.5)

0.298

5.3

(0.5)

5.2

(0.5)

0.614

5.3

(0.5)

5.2

(0.4)

0.639

HbA1c

34.3

(4.0)

36.7

(4.5)

0.028

35.3

(3.2)

35.2

(4.8)

0.945

35.1

(4.2)

35.5

(4.6)

0.677

35.6

(3.6)

34.7

(5.6)

0.429

Systolic BP

128.4

(13.3)

128.2

(14.2)

0.933

127.1

(12.9)

128.9

(14.0)

0.596

127.0

(12.0)

130.5

(15.8)

0.298

128.4

(13.9)

128.2

(13.2)

0.945

Diastolic BP

77.9

(9.3)

82.3

(10.2)

0.065

78.1

(10.6)

80.7

(9.5)

0.297

77.7

(8.7)

83.2

(10.8)

0.021

78.9

(10.1)

81.3

(9.5)

0.333

ABI

1.1

(0.1)

1.1

(0.2)

0.296

1.1

(0.1)

1.1

(0.1)

0.332

1.1

(0.1)

1.1

(0.1)

0.592

1.1

(0.1)

1.1

(0.1)

0.909

HOMAir

1.1

(0.4–6.5)

1.6

(0.2–6.6)

0.095

1.1

(0.4–6.5)

1.2

(0.2–6.6)

0.417

1.1

(0.4–6.5)

1.2

(0.2–6.6)

0.597

1.0

(0.2–6.6)

1.3

(0.4–5.8)

0.162

  1. BMI Body mass index, HDL High-density lipoprotein, LDL Low-density lipoprotein, BP Blood pressure, ABI Ankle brachial index, HOMA-ir Homeostatic Model Assessment for insulin resistance. Normally distributed variables are described by mean (SD), and non-normally distributed variables are described by median (range)