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Table 1 Patient Characteristics before NAC

From: Impact of neoadjuvant intensity-modulated radiation therapy on borderline resectable pancreatic cancer with arterial abutment; a prospective, open-label, phase II study in a single institution

Pre NACIMRT (at enrollment)

n = 49

age (years)

68.6(46.0–77.8)

gender (male/female)

29/20

head/body-tail

32/17

radiographic arterial involvement

 

celiac artery

4

common hepatic artery

9

replaced RHA

2

superior mesenteric artery

34

BRPV/without BRPV

28/21

radiological tumor size (mm)

25.7(15.0–47.0)

CEA before NACIMRT (U/ml)

3.0(0.5–114.9)

CA19-9 before NACIMRT (U/ml)

111.4(0.6–2451)

NL ratio before NACIMRT

2.55(1.0–10.0)

SUV max before NACIMRT

6.4(2.2–15.8)

NAC incompletion due to adverse event

2/49(4.1%)

Post NACIMRT (at re-assessment after NACIMRT)

n = 47

radiological tumor size after NACIMRT (mm)

21.5(11.7–50.1)

CEA after NACIMRT (U/ml)

3.0(0.7–57.6)

CA19-9 after NACIMRT (U/ml)

36.7(0.6–2298)

NL ratio after NACIMRT

3.04(0.81–11.86)

SUV max after NACIMRT

4.35(1.9–10.4)

RECIST > PR

13/47(27.6%)

G3/4 adverse event

10/47(21.3%)

  1. Abbreviations: NAC neoadjuvant therapy, IMRT Intensity Modulated Radiation Therapy, RHA right hepatic artery, BRPV borderline resectable pancreatic cancer with portal vein involvement, CEA carcinoembryonic antigen, CA19-9 carbohydrate antigen 19–9, NL ratio, neutrophil to lymphocyte ratio, SUV max, maximum standard uptake value