Table 2 Genetic loci significantly associated with tumor markers (8 indicators) identified by the GWAS after imputation analysis in the Han population from Southern China

AFP

LOC100287704/LOC100287834

rs1524622

7

63375308

C/T

C

0.163

intronic

0.424

0.090

3.59E-06

SGCZ

rs143687479

8

14561503

C/T

C

0.004

intronic

2.585

0.552

3.86E-06

ZNF444/GALP

rs10425983

19

56167810

A/G

A

0.006

intergenic

-1.995

0.430

4.67E-06

CA50

RBFOX2/APOL3

rs112401204

22

36114041

T/C

T

0.073

intergenic

-0.750

0.150

1.12E-06

LINC00533/LINC01623

rs9295778

6

28716406

T/G

T

0.062

intergenic

0.782

0.157

1.15E-06

CA125

GCFC2/LRRTM4

rs75332508

2

76156698

T/C

T

0.013

intergenic

-1.545

0.297

3.10E-07

LINC01790/SLC39A10

rs12476806

2

195329086

C/T

C

0.175

intergenic

0.396

0.084

3.25E-06

D2HGDH/GAL3ST2

rs7563672

2

241773455

T/G

T

0.358

intergenic

-0.306

0.065

3.70E-06

LOC728613/MIR4277

rs6554915

5

1639786

C/T

C

0.129

intergenic

0.487

0.103

2.88E-06

CDK17/CFAP54

rs2028385

12

96423644

G/A

G

0.289

intergenic

0.357

0.071

6.67E-07

CA153

MUC1

rs4072037

1

155192276

C/T

C

0.161

exonic

1.097

0.110

1.28E-18

PCDH7

rs112804057

4

30878623

G/C

G

0.021

intronic

1.651

0.339

2.61E-06

LOC100128317

rs12113394

7

81597863

G/A

G

0.197

ncRNA_intronic

0.692

0.126

1.45E-07

PTDSS1/LOC102724804

rs7838015

8

96340364

C/T

C

0.140

intergenic

0.699

0.144

2.86E-06

ABO

rs1053878

9

133256264

A/G

A

0.164

exonic

-0.646

0.129

1.33E-06

KCNH5

rs8015097

14

62895145

G/C

G

0.321

intronic

-0.473

0.098

3.44E-06

RASGEF1C

rs62406978

5

180204890

T/A

T

0.016

intronic

1.895

0.397

4.12E-06

CA19-9

DPP10

rs67300776

2

115190571

T/G

T

0.347

intronic

-0.322

0.069

4.41E-06

ADAMTS9-AS2/MAGI1

rs1482587

3

65151572

C/T

C

0.491

intergenic

0.327

0.066

9.00E-07

ADRA1B/TTC1

rs147309725

5

160000916

A/G

A

0.097

intergenic

-0.543

0.115

3.05E-06

LOC389602/LOC285889

rs4716999

7

156160296

C/T

C

0.382

intergenic

-0.360

0.071

6.50E-07

CEA

TMEM132D

rs11060471

12

129627766

T/C

T

0.326

intronic

-0.349

0.071

1.25E-06

FARP1

rs17568726

13

98361516

C/G

C

0.310

intronic

-0.352

0.073

1.99E-06

f-PSA

PDE4B

rs72641143

1

66233311

C/T

C

0.081

intronic

-0.798

0.170

4.78E-06

PAM

rs466235

5

102762878

C/T

C

0.443

intronic

-0.453

0.095

3.06E-06

PCAT5/ANKRD30A

rs78255505

10

37091392

C/T

C

0.063

intergenic

-0.892

0.185

2.67E-06

PABPN1L/CBFA2T3

rs113984953

16

88872490

A/G

A

0.128

intergenic

-0.641

0.134

2.96E-06

ERG

rs4816598

21

38551999

T/C

T

0.167

intronic

-0.614

0.123

1.22E-06

SCC-Ag

MIR6072/LINC00701

rs111241781

10

2077191

C/T

C

0.035

intergenic

0.917

0.187

1.37E-06

HNF4G/LINC01111

rs117089993

8

75885175

T/A

T

0.025

intergenic

0.991

0.212

4.10E-06

SHISA9/ERCC4

rs72773580

16

13562027

A/G

A

0.040

intergenic

-0.878

0.173

6.24E-07