Table 1 Associations between the expression of C12orf48 with clinicopathological features in 109 patients with gastric cancer
Parameter | Total (n = 109) | Number of cases | P-value | |
|---|---|---|---|---|
Negative | Positive | |||
Age at diagnosis (years) | ||||
< 60 | 35 | 20 (57.1%) | 15 (42.9%) | 0.413 |
≥ 60 | 74 | 35 (47.3%) | 39 (52.7%) | |
Gender | ||||
Male | 87 | 44 (50.6%) | 43 (49.4%) | 0.575 |
Female | 22 | 11 (50.0%) | 11 (50.0%) | |
Histological subtypes | ||||
Well + Moderately differentiated | 65 | 35 (53.8%) | 30 (46.2%) | 0.438 |
Poorly differentiated + Signet ring cell | 44 | 20 (45.5%) | 24 (54.5%) | |
Depth of invasion | ||||
T 1 + 2 | 14 | 11 (78.6%) | 3 (21.4%) | 0.042 |
T 3 + 4 | 95 | 44 (46.3%) | 51 (53.7%) | |
Vessel Cancer Embolus | ||||
No | 92 | 48 (52.2%) | 44 (47.8%) | 0.698 |
Yes | 17 | 7 (41.2%) | 10 (58.8%) | |
Perineural invasion | ||||
No | 90 | 50 (55.6%) | 40 (44.4%) | 0.024 |
Yes | 19 | 5 (26.3%) | 14 (73.7%) | |
Nodal metastasis | ||||
No | 31 | 21 (67.1%) | 10 (32.9%) | 0.033 |
Yes | 78 | 34 (43.6%) | 44 (56.4%) | |
pTNM stage | ||||
I/II | 39 | 23 (59.0%) | 16 (41.0%) | 0.184 |
III/IV | 70 | 32 (45.7%) | 38 (54.3%) | |
Tumour size(cm) | ||||
< 6 | 63 | 32 (50.8%) | 31 (49.2%) | 1.000 |
≥ 6 | 46 | 23 (50.0%) | 23 (50.0%) | |