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Table 3 Univariable and multivariable Cox regression analyses for prognostic factors in patients from Sun Yat-sen University Cancer Center cohort before propensity score matching

From: Postoperative survival effect of the number of examined lymph nodes on esophageal squamous cell carcinoma with pathological stage T1–3N0M0

  Univariable analyses Multivariable analyses
HR 95% CI P-Value HR 95% CI P-Value
Sex
 Male 1 reference   1 reference  
 Female 0.935 0.733–1.193 0.590 0.876 0.664–1.155 0.349
Age (years)
  ≤ 60 1 reference   1 reference  
  > 60 1.342 1.083–1.662 0.007 1.264 1.018–1.569 0.034
Drinking history
 No 1 reference   1 reference  
 Yes 1.421 1.134–1.780 0.002 1.673 1.303–2.149 < 0.001
Tumor length (continuous) 1.007 0.941–1.078 0.832    
NELNs
  ≤ 15 1 reference   1 reference  
  > 15 0.630 0.506–0.784 < 0.001 0.566 0.445–0.720 < 0.001
Tumor differentiation
 Well 1 reference   1 reference  
 Moderate 1.088 0.833–1.420 0.537 1.057 0.808–1.383 0.687
 Poor 1.500 1.110–2.026 0.008 1.812 1.334–2.461 < 0.001
pT stage
 T1 1 reference   1 reference  
 T2 1.132 0.776–1.652 0.520 1.236 0.840–1.819 0.283
 T3 1.584 1.130–2.221 0.008 1.856 1.312–2.626 < 0.001
Tumor Location
 Upper 1 reference   1 reference  
 Middle 0.960 0.665–1.386 0.828 0.899 0.605–1.305 0.547
 Lower 0.659 0.460–0.946 0.024 0.491 0.331–0.729 < 0.001
Smoking history
 No 1 reference     
 Yes 1.087 0.871–1.358 0.461    
Surgical approaches
 Sweet 1 reference   1 reference  
 Ivor-Lewis 1.922 1.174–3.144 0.009 1.568 0.948–2.595 0.080
 McKeown 0.782 0.602–1.017 0.066 0.749 0.543–1.033 0.078
 Other 0.790 0.390–1.599 0.512 0.815 0.400–1.661 0.573
Transthoracic laterality
 Left 1 reference     
 Right 0.856 0.673–1.088 0.204    
 Other 0.879 0.218–3.536 0.855    
Two-field dissection
 No 1 reference   1 reference  
 Yes 0.979 0.687–1.396 0.907 0.930 0.543–1.593 0.791
Three-field dissection
 No 1 reference   1 reference  
 Yes 1.063 0.669–1.689 0.797 1.366 0.658–2.836 0.403
  1. HR hazard ratio, CI confidence interval, NELN the number of examined lymph node; Cox regression’s method was Enter selection