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Table 1 Clinicopathological characteristic of patients from Sun Yat-sen University Cancer Center database before and after propensity score matching

From: Postoperative survival effect of the number of examined lymph nodes on esophageal squamous cell carcinoma with pathological stage T1–3N0M0

 

Entire cohort (N = 707)

 

Matched cohort (N = 462)

 

NELNs ≤15

(N = 352)

NELNs > 15

(N = 355)

NELNs ≤15

(N = 231)

NELNs > 15

(N = 231)

Variables

  

P value

  

P value

 Sex, n (%)

  

0.360*

  

0.212*

  Male

251 (71.3%)

264 (74.4%)

173 (74.9%)

161 (69.7%)

 

  Female

101 (28.7%)

91 (25.6%)

58 (25.1%)

70 (30.3%)

 

 Drinking history, n (%)

  

0.001*

  

0.761*

  No

271 (77.0%)

235 (66.2%)

163 (70.6%)

160 (69.3%)

 

  Yes

81 (23.0%)

120 (33.8%)

68 (29.4%)

71 (30.7%)

 

 Smoking history, n (%)

  

0.004*

  

0.774*

  No

152 (43.2%)

116 (32.7%)

 

87 (37.7%)

90 (39.0%)

 

  Yes

200 (56.8%)

239 (67.3%)

 

144 (62.3%)

141 (61.0%)

 

 Tumor differentiation, n (%)

  

0.373*

  

0.318*

  Well

84 (23.9%)

96 (27.0%)

 

54 (23.4%)

60 (26.0%)

 

  Moderate

192 (54.5%)

175 (49.3%)

 

126 (54.5%)

110 (47.6%)

 

  Poor

76 (21.6%)

84 (23.7%)

 

51 (22.1%)

61 (26.4%)

 

 pT stage, n (%)

  

0.033*

  

0.955*

  T1

60 (17.0%)

47 (13.2%)

35 (15.2%)

37 (16.0%)

 

  T2

107 (30.4%)

87 (24.5%)

56 (24.2%)

54 (23.4%)

 

  T3

185 (52.6%)

221 (62.3%)

140 (60.6%)

140 (60.6%)

 

 Surgical approaches, n (%)

  

< 0.001*

  

0.095**

  Sweet

287 (81.5%)

194 (54.6%)

 

178 (77.1%)

179 (77.5%)

 

  Ivor-Lewis

15 (4.3%)

9 (2.5%)

 

10 (4.3%)

9 (3.9%)

 

  McKeown

37 (10.5%)

145 (40.8%)

 

33 (14.3%)

41 (17.7%)

 

  Other

13 (3.7%)

7 (2.1%)

 

10 (4.3%)

2 (0.9%)

 

 Transthoracic laterality, n (%)

  

< 0.001**

  

0.735**

  Left

293 (83.2%)

196 (55.2%)

 

182 (78.8%)

179 (77.5%)

 

  Right

57 (16.2%)

156 (43.9%)

 

48 (20.8%)

52 (22.5%)

 

  Other

2 (0.6%)

3 (0.9%)

 

1 (0.4%)

0 (0.0%)

 

 Two-field dissection, n (%)

  

0.093*

  

1.000*

  No

30 (8.5%)

44 (12.4%)

 

7 (3.0%)

8 (3.5%)

 

  Yes

322 (91.5%)

311 (97.6%)

 

224 (97.0%)

223 (96.5%)

 

 Three-field dissection, n (%)

  

< 0.001**

  

1.000**

  No

349 (99.1%)

316 (89.0%)

 

228 (98.7%)

227 (98.3%)

 

  Yes

3 (0.9%)

39 (11.0%)

 

3 (1.3%)

4 (1.7%)

 

 Tumor location, n (%)

  

0.647*

  

0.776*

  Upper

31 (8.8%)

36 (10.1%)

14 (6.1%)

12 (5.2%)

 

  Middle

123 (34.9%)

131 (36.9%)

76 (32.9%)

83 (35.9%)

 

  Lower

198 (56.3%)

188 (53.0%)

141 (61.0%)

136 (58.9%)

 

 Age (year), n (%)

  

0.312*

  

0.453*

   ≤ 60

196 (55.7%)

211 (59.4%)

 

134 (58.0%)

126 (54.5%)

 

   > 60

156 (44.3%)

144 (40.6%)

 

97 (42.0%)

105 (45.5%)

 

 Median (interquartile range)

59 (14)

59 (12)

0.972***

59 (15)

60 (12)

0.082***

 Tumor length (cm)

  

0.013**

  

0.705*

   ≤ 3

192 (55.2%)

162 (45.8%)

 

107 (46.9%)

112 (48.7%)

 

   > 3

156 (44.8%)

192 (54.2%)

 

121 (53.1%)

118 (51.3%)

 

 Median (interquartile range)

3.0 (2.0)

3.5 (2.5)

0.001***

3.5 (2.0)

3.5 (2.5)

0.776***

  1. NELN the number of examined lymph node; *: chi-squared test; **: Fisher’s exact test; ***: Mann-Whitney U test
  2. There were 5 patients with missing data in tumor length