Fig. 3
Random-effects meta-analysis of the hazard ratio of progression-free survival (A) and overall survival (B) comparing weekly and three-weekly docetaxel schedules; squares demonstrate the point estimate of the hazard ratio; lines represent the 95% CI; the size of each square is proportional to its weight in meta-analysis; diamonds represent the pooled estimate of the hazard ratio after meta-analysis; values < 1 indicate a lower chance of progression/death in the three-weekly arm as opposed to the weekly arm while values > 1 indicate a lower chance of progression/death in the weekly arm; I2 measure of statistical heterogeneity with the corresponding p-value a test for heterogeneity across studies; τ2 variance of the distribution of the observed study effects