Table 1 Correlation between the PFKFB3 level and the overall survival of ccRCC patients

 Age (≥60 vs <60)

1.875

1.152-3.149

0.015

 Gender (Male vs Female)

1.267

0.589-2.627

0.365

 TNM stage (III/IV vsI/II)

3.396

2.133-5.548

<0.001

 Furhman grade (III/IV vsI/II)

2.376

1.116-4.385

0.003

 PFKFB3 (High vs Low)

1.715

1.232-2.540

<0.001

 Age (≥60 vs <60)

1.394

0.925-2.214

0.065

 TNM stage (III/IV vsI/II)

2.674

1.878-3.794

<0.001*

 Furhman grade (III/IV vsI/II)

1.751

1.130-2.812

0.009*

 PFKFB3 (High vs Low)

1.358

1.028-2.791

<0.001*