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Table 3 Estimated power based on cohort and sample size

From: The MITRE trial protocol: a study to evaluate the microbiome as a biomarker of efficacy and toxicity in cancer patients receiving immune checkpoint inhibitor therapy

 

100

150

200

300

400

600

Melanoma Nivo

1 year PFS

0.650

0.682

0.710

0.738

0.754

0.759

Melanoma Nivo+IPI

1 year PFS

0.754

0.766

0.775

0.784

0.788

0.795

NSCLC Pembrolizumab

1 year PFS

0.732

0.750

0.764

0.776

0.782

0.790