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Table 2 Univariable and Multivariate analysis for PFS and OS in 131 de novo mNPC patients

From: Optimizing the treatment mode for de novo metastatic nasopharyngeal carcinoma with bone-only metastasis

  Univariable Multivariable
HR (95% CI) p HR (95% CI) p
Progress-free survival
 Age (≤ 50 vs > 50) 1.184 (0.742–1.889) 0.479   
 Sex (Female vs Male) 0.925 (0517–1.655) 0.792   
 Chemotherapy cycles (< 4 vs ≥ 4) 0298 (0.186–0.477) <  0.001 0.370 (0.215–0.638) <  0.001
 IMRT (No vs Yes) 0.480 (0.303–0.759) 0.002 0.785 (0.461–1.336) 0.371
 No. of bone metastasis (≤ 5 vs > 5) 0.503 (0.316–0.800) 0.004 0.597 (0.383–0.930) 0.053
 RT to bone metastases (No vs Yes) 0.988 (0.620–1.577) 0.961   
Overall Survival
 Age (≤ 50 vs > 50) 1.600 (1.009–2.537) 0.046 1.484 (0.929–2.372) 0.099
 Sex (Female vs Male) 1.010 (0.572–1.781) 0.973   
 Chemotherapy cycles (< 4 vs ≥ 4) 0.269 (0.170–0.425) <  0.001 0.379 (0.224–0.639) <  0.001
 IMRT (No vs Yes) 0.374 (0.235–0.595) <  0.001 0.624 (0.369–1.054) 0.078
 No. of bone metastasis (≤ 5 vs > 5) 0.449 (0.282–0.715) 0.001 0.567 (0.352–0.915) 0.020
 RT to bone metastases (No vs Yes) 0.914 (0.572–1.459) 0.706