Table 1 Patients’ clinicopathological parameters and correlation with TAMs
| Parameters |
High CD68 (%) N = 123 |
LOW CD68 (%) N = 149 | χ2 value | P value |
High CD163 (%) N = 125 |
LOW CD163 (%) N = 147 | χ2 value | P value |
|---|---|---|---|---|---|---|---|---|
| Age | 2.469 | 0.116 | 0.773 | 0.379 | ||||
| ≤ 45 | 43 (35.0) | 39 (26.2) | 41 (32.8) | 41 (27.9) | ||||
| >45 | 80 (65.0) | 110 (73.8) | 84 (67.2) | 106 (72.1) | ||||
| Tumor size | 0.925 | 0.819 | 2.522 | 0.471 | ||||
| T1 | 38 (30.9) | 52 (34.9) | 36 (28.8) | 54 (36.7) | ||||
| T2 | 76 (61.8) | 89 (59.7) | 80 (64) | 85 (57.8) | ||||
| T3 | 6 (4.9) | 6 (4.0) | 7 (5.6) | 5 (3.4) | ||||
| T4 | 3 (2.4) | 2 (1.3) | 2 (1.6) | 3 (2.0) | ||||
| Axillary metastasis | 1.544 | 0.672 | 1.783 | 0.619 | ||||
| N0 | 58 (47.2) | 79 (53.0) | 62 (49.6) | 75 (51.0) | ||||
| N1 | 33 (26.9) | 35 (23.5) | 28 (22.4) | 40 (27.2) | ||||
| N2 | 20 (16.3) | 25 (16.8) | 24 (19.2) | 21 (14.3) | ||||
| N3 | 12 (9.8) | 10 (6.7) | 11 (8.8) | 11 (7.5) | ||||
| Hormonal receptor | 2.177 | 0.140 | 3.622 | 0.057 | ||||
| Positive | 88 (71.5) | 94 (63.1) | 91 (72.8) | 91 (61.9) | ||||
| Negative | 35 (28.5) | 55 (36.9) | 34 (27.2) | 56 (38.1) | ||||
| Her-2 | 2.420 | 0.120 | 3.007 | 0.083 | ||||
| Positive | 30 (24.4) | 25 (16.8) | 31 (24.8) | 24 (16.3) | ||||
| Negative | 93 (75.6) | 124 (83.2) | 94 (75.2) | 123 (83.7) | ||||
| Microcalcifications | 9.141 | 0.002 | 28.060 | 0.000 | ||||
| With microcalcifications | 46 (37.4) | 31 (20.8) | 55 (44.0) | 22 (15.0) | ||||
| Without microcalcifications | 77 (62.6) | 118 (79.2) | 70 (56.0) | 125 (85.0) | ||||
| Follow up (month) | 116 | 115 | 115 | 115 | ||||
| Recurrence | 24 | 20 | 29 | 15 |