Fig. 2

miR-615 was poorly expressed in CRC, and overexpression of miR-615 inhibited the growth of CRC cells. A miR-615 expression of normal colorectal tissues and CRC tissues was detected using RT-qPCR, N = 27. B miR-615 expression of normal colon epithelial cells and CRC cells was detected using RT-qPCR. C,D The cell growth in each group was measured using MTT assay and colony formation assay. E The cell invasion was measured using Transwell assay. F The cell apoptosis was detected using flow cytometry. The cell experiments were repeated 3 times independently. Data are presented as mean ± standard deviation. Data in panels A/D/E/F/G were analyzed using t test, and data in panel B and C were analyzed using one-way ANOVA, followed by Tukey’s multiple comparisons test. *p < 0.05 vs. the normal, NCM460 or mimic NC groups