Table 2 Various features in the group of patients studied with respect to CRC outcome
CRC outcome Variable | Recovered = 234 Number (%) | Deceased = 59 Number (%) | Total = 293 Number (%) | P-value |
|---|---|---|---|---|
Continuous age - mean (SD) | 53.58 (14.11) | 59.25 (16.88) | 54.72 (14.86) | 0.009 |
Age range (years) | ||||
 20–29 | 8 (3.4) | 3 (5.1) | 11 (3.8) |  |
 30–39 | 31 (13.2) | 6 (10.2) | 37 (12.6) |  |
 40–49 | 55 (23.5) | 8 (13.6) | 63 (21.5) | 0.03d |
 50–59 | 57 (24.4) | 11 (18.6) | 68 (23.2) |  |
 60–69 | 40 (17.1) | 10 (16.9) | 50 (17.1) |  |
 70–79 | 35 (15.0) | 13 (22.0) | 48 (16.4) |  |
  ≥ 80 | 8 (3.4) | 8 (13.6) | 16 (5.5) |  |
Gender | ||||
 Female | 156 (49.0) | 29 (49.0) | 185 (49.0) | 0.9c |
 Male | 159 (51.0) | 30 (51.0) | 189 (51.0) |  |
Amsterdam II | ||||
 Criteria absent | 196 (95.1) | 53 (96.3) | 249 (95.0) | 0.7c |
 Criteria present | 10 (4.9) | 2 (3.7) | 12 (5.0) |  |
Tumour location | ||||
 Proximal | 30 (14.2) | 6 (10.9) | 36 (13.5) | 0.2c |
 Distal | 126 (59.4) | 28 (50.9) | 154 (57.7) |  |
 Rectum | 56 (26.4) | 21 (38.2) | 77 (28.8) |  |
Mismatch repair status | ||||
 Proficient | 143 (92.0) | 31 (77.5) | 174 (89.0) | 0.02c |
 Deficient | 13 (8.0) | 9 (22.5) | 22 (11.0) |  |
At high risk for LSa | ||||
 No | 145 (93.0) | 32 (80.0) | 177 (90.0) | 0.03c |
 Yes | 11 (7.0) | 8 (20.0) | 19 (10.0) |  |
MLH1 | ||||
 pMMR | 147 (94.0) | 34 (85.0) | 181 (92.0) | 0.05c |
 dMMR | 9 (6.0) | 6 (15.0) | 15 (8.0) |  |
PMS2 | ||||
 pMMR | 145 (94.0) | 33 (82.0) | 178 (91.0) | 0.02c |
 dMMR | 10 (6.0) | 7 (18.0) | 17 (9.0) |  |
MSH2 | ||||
 pMMR | 152 (98.0) | 38 (95.0) | 190 (97.0) | 0.27c |
 dMMR | 3 (2.0) | 2 (5.0) | 5 (3.0) |  |
MSH6 | ||||
 pMMR | 153 (98.0) | 38 (95.0) | 191 (97.0) | 0.27c |
 dMMR | 3 (2.0) | 2 (5.0) | 5 (3.0) |  |