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Table 1 Patient characteristics

From: Trastuzumab and fulvestrant combination therapy for women with advanced breast cancer positive for hormone receptor and human epidermal growth factor receptor 2: a retrospective single-center study

Characteristics

N = 28 (%)

Age (years)

  median

66 (range: 50–80)

Stage

  De novo stage IV

7 (25)

  recurrent disease

21 (75)

Subtype

  HR+ HER2+

28 (100)

  others

0

Number of treatment line

  median

6

  1 or 2

6 (21)

  3–6

9 (32)

  7–10

9 (32)

  > 10

4 (14)

Prior treatment for recurrent or metastatic breast cancer

  Trastuzumab

28 (100)

  Pertuzumab

4 (14)

  T-DM1

10 (36)

  Trastuzumab deruxtecan (T-DXd)

2 (7)

Visceral metastasis

  Yes

21 (75)

  No

7 (25)

Liver metastasis

  Yes

11 (39)

  No

17 (61)

Brain metastasis

  Yes

4 (14)

  No

24 (86)