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Table 2 Cumulative PPV/Sensitivity/Specificity (%) for CIN2+ in the triage of hrHPV-positive women

From: Roles of extended human papillomavirus genotyping and multiple infections in early detection of cervical precancer and cancer and HPV vaccination

hrHPV types

Primary type

For the new type

CIN2+/HPV+

Cumulative types

PPV (%)

CIN2+/HPV+

PPV (%)

PPV (%)

SEN (%)

SPE (%)

16

27.4

279/1020

27.4

279/1020

27.4

63.8

67.8

33

26.0

28/119

23.5

307/1139

27.0

70.3

63.8

35

17.6

10/59

16.9

317/1198

26.5

72.5

61.7

58

18.2

46/292

15.8

363/1490

24.4

83.1

51.0

31

16.8

18/127

14.2

381/1617

23.6

87.2

46.2

68

9.9

8/121

6.6

389/1738

22.4

89.0

41.3

18

8.3

16/265

6.0

405/2003

20.2

92.7

30.5

56

10.4

5/84

6.0

410/2087

19.6

93.8

27.0

52

11.7

15/270

5.6

425/2357

18.0

97.3

15.9

66

5.7

4/74

5.4

429/2431

17.6

98.2

12.9

51

7.2

5/131

3.8

434/2562

16.9

99.3

7.4

59

7.9

2/56

3.6

436/2618

16.7

99.8

5.0

45

10.3

1/32

3.1

437/2650

16.5

100.0

3.7

39

4.9

0/85

0.0

437/2735

16.0

100.0

0.0

  1. Abbreviations: CIN2+ cervical intraepithelial neoplasia 2 or worse, SEN sensitivity, SPE specificity, PPV positive predictive value