Table 2 Univariate and multivariate analyses of factors determining overall survival in the entire cohort

Treatment

 Microwave ablation

1.15 (0.76–1.74)

0.51

 Radiofrequency ablation

1.00 (Reference)

Age per 10 years

1.15 (0.94–1.4)

0.17

Gender

 Male

1.31 (0.91–1.9)

0.15

 Female

1.0 (Reference)

Cirrhosis

 Yes

1.47 (0.72–3.02)

0.29

 No

1.00 (Reference)

Etiology of Liver Disease

 HCV (positive HCV RNA)

1.38 (0.54–3.54)

0.5

 HCV (negative HCV RNA)

0.97 (0.33–2.9)

0.96

 Non-alcoholic fatty liver

1.74 (0.67–4.52)

0.25

 Alcoholic Liver disease

1.47 (0.55–3.92)

0.44

 Others

0.87 (0.33–2.28)

0.77

 HBV

1.00 (Reference)

Child Pugh score

 B

2.39 (1.64–3.49)

< 0.001

 A

1.00 (Reference)

Portal Hypertension

 Yes

1.61 (1.11–2.34)

0.012

 No

1.00 (Reference)

Tumor size per 1 unit

1.15 (1.012–1.31)

0.032

0.031

Tumor number per 1 tumor

1.29 (1.088–1.53)

0.003

0.015

BCLC Stage

 A

3.00 (1.31–6.86)

0.009

 B

5.80 (2.26–14.9)

< 0.001

 0

1.00 (Reference)

MELD Score per point

1.08 (1.034–1.12)

< 0.001

< 0.0001 

Hyperlipidemia

 Yes

1.05 (0.68–1.62)

0.83

 No

1.00 (Reference)

Hypothyroidism

 Yes

1.06 (0.69–1.61)

0.8

 No

1.00 (Reference)

Log² AFP

1.04 (0.97–1.11)

0.32

Glucose (mg/dl)

1.00 (0.99–1.005)

0.49

Pre-ablation NLR per unit increase

1.17 (1.058–1.28)

0.002

Pre-ablation PLR

1.03 (0.74–1.45)

0.85

Pre-ablation LMR per unit increase

0.72 (0.61–0.86)

< 0.001

0.0001