Variable | Univariate | Multivariate | ||||
---|---|---|---|---|---|---|
HR (95% CI) | overall P | P | HR (95% CI) | overall P | P | |
Treatment | ||||||
 Microwave ablation | 1.15 (0.76–1.74) |  | 0.51 |  |  |  |
 Radiofrequency ablation | 1.00 (Reference) |  |  |  |  |  |
Age per 10 years | 1.15 (0.94–1.4) |  | 0.17 |  |  |  |
Gender | ||||||
 Male | 1.31 (0.91–1.9) |  | 0.15 |  |  |  |
 Female | 1.0 (Reference) |  |  |  |  |  |
Cirrhosis | ||||||
 Yes | 1.47 (0.72–3.02) |  | 0.29 |  |  |  |
 No | 1.00 (Reference) |  |  |  |  |  |
Etiology of Liver Disease | Â | 0.17 | Â | Â | Â | Â |
 HCV (positive HCV RNA) | 1.38 (0.54–3.54) |  | 0.5 |  |  |  |
 HCV (negative HCV RNA) | 0.97 (0.33–2.9) |  | 0.96 |  |  |  |
 Non-alcoholic fatty liver | 1.74 (0.67–4.52) |  | 0.25 |  |  |  |
 Alcoholic Liver disease | 1.47 (0.55–3.92) |  | 0.44 |  |  |  |
 Others | 0.87 (0.33–2.28) |  | 0.77 |  |  |  |
 HBV | 1.00 (Reference) |  |  |  |  |  |
Child Pugh score | ||||||
 B | 2.39 (1.64–3.49) |  | < 0.001 |  |  |  |
 A | 1.00 (Reference) |  |  |  |  |  |
Portal Hypertension | ||||||
 Yes | 1.61 (1.11–2.34) |  | 0.012 |  |  |  |
 No | 1.00 (Reference) |  |  |  |  |  |
Tumor size per 1 unit | 1.15 (1.012–1.31) |  | 0.032 | 1.18 (1.015–1.37) |  | 0.031 |
Tumor number per 1 tumor | 1.29 (1.088–1.53) |  | 0.003 | 1.23 (1.041–1.46) |  | 0.015 |
BCLC Stage | Â | 0.0009 | Â | Â | Â | Â |
 A | 3.00 (1.31–6.86) |  | 0.009 |  |  |  |
 B | 5.80 (2.26–14.9) |  | < 0.001 |  |  |  |
 0 | 1.00 (Reference) |  |  |  |  |  |
MELD Score per point | 1.08 (1.034–1.12) |  | < 0.001 | 1.12 (1.068–1.17) |  | < 0.0001  |
Hyperlipidemia | ||||||
 Yes | 1.05 (0.68–1.62) |  | 0.83 |  |  |  |
 No | 1.00 (Reference) |  |  |  |  |  |
Hypothyroidism | ||||||
 Yes | 1.06 (0.69–1.61) |  | 0.8 |  |  |  |
 No | 1.00 (Reference) |  |  |  |  |  |
Log2 AFP | 1.04 (0.97–1.11) |  | 0.32 |  |  |  |
Glucose (mg/dl) | 1.00 (0.99–1.005) |  | 0.49 |  |  |  |
Pre-ablation NLR per unit increase | 1.17 (1.058–1.28) |  | 0.002 |  |  |  |
Pre-ablation PLR | 1.03 (0.74–1.45) |  | 0.85 |  |  |  |
Pre-ablation LMR per unit increase | 0.72 (0.61–0.86) |  | < 0.001 | 0.7 (0.58–0.84) |  | 0.0001 |