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Table 1 Baseline Characteristics for the ablation groups

From: Prognostic utility of systemic inflammatory markers and chronic hepatitis C virus infection status in hepatocellular carcinoma patients treated with local ablation

 

MWA

(N = 81)

RFA

(N = 140)

Total

(N = 221)

P-value

Age, years

   

0.81

 Mean ± SD

68.5 ± 8.1

67.6 ± 10.4

67.9 ± 9.6

 

Gender, no. (%)

   

0.0822

 Female

23 (28.4%)

56 (40%)

79 (35.7%)

 

 Male

58 (71.6%)

84 (60%)

142 (64.3%)

 

Cirrhosis, no. (%)

   

0.522

 No

5 (6.2%)

12 (8.6%)

17 (7.7%)

 

 Yes

76 (93.8%)

128 (91.4%)

204 (92.3%)

 

Underlying Liver Disease, no. (%)

   

0.142

 Hepatitis C virus

27 (33.3%)

56 (40%)

83 (37.6%)

 

 Non-alcoholic fatty liver

26 (32.1%)

25 (17.9%)

51 (32.1%)

 

 Alcoholic Liver disease

12 (14.8%)

22 (15.7%)

34 (15.4%)

 

 Hepatitis B virus

5 (6.2%)

7 (5%)

12 (5.4%)

 

 Others

11 (13.6%)

30 (21.4%)

41 (18.6%)

 

Portal Hypertension, no. (%)

   

0.662

 No

30 (37%)

56 (40%)

86 (38.9%)

 

 Yes

53 (65.4%)

97 (61.4%)

188 (63.7%)

 

Child Pugh score, no. (%)

   

0.52

 A

58 (71.6%)

106 (75.7%)

164 (74.2%)

 

 B

23 (28.4%)

34 (24.3%)

57 (25.8%)

 

Tumor Size

   

0.511

 Mean ± SD

2.2 ± 0.6

2.3 ± 1.2

2.3 ± 1

 

Tumors Number, no. (%)

   

0.0121

 = 1

66 (81.5%)

96 (68%)

162 (73.3%)

 

 = 2

10 (12.3%)

29 (20.7%)

39 (17.6%)

 

 = 3

4 (4.9%)

8 (5.7%)

12 (5.4%)

 

 > 3

1 (1.2%)

7 (5%)

8 (3.7%)

 

BCLC Staging, no. (%)

   

0.00082

 0

2 (2.5%)

15 (10.7%)

17 (7.7%)

 

 A

77 (95.1%)

105 (75%)

182 (82.4%)

 

 B

2 (2.5%)

20 (14.3%)

22 (10%)

 

Hyperlipidemia, no. (%)

   

0.0222

 No

55 (67.9%)

114 (81.4%)

169 (76.5%)

 

 Yes

26 (32.1%)

26 (18.6%)

52 (23.5%)

 

Hypothyroidism, no. (%)

   

0.732

 No

65 (81.5%)

115 (82.1%)

180 (81.4%)

 

 Yes

16 (19.8%)

25 (17.9%)

41 (18.6%)

 

AFP

   

0.261

 Mean ± SD

44.3 ± 118.9

84.7 ± 329.9

70.1 ± 273.4

 

Cholesterol (mg/dl)

   

0.691

 Mean ± SD

152.7 ± 34.7

154.7 ± 69.9

154.1 ± 61.3

 

Triglycerides (mg/dl)

   

0.31

 Mean ± SD

107.8 ± 46

107.2 ± 70.3

107.4 ± 63.8

 

HDL (mg/dl)

   

0.911

 Mean ± SD

47.7 ± 18.9

48.1 ± 16.3

48 ± 17

 

LDL (mg/dl)

   

0.891

 Mean ± SD

83.0 ± 30.8

82.4 ± 33.2

82.6 ± 32.3

 

Glucose (mg/dl)

   

0.771

 Mean ± SD

104.7 ± 47.2

109 ± 50.4

107.9 ± 49.5

 

HB A1c

   

0.31

 Mean ± SD

6.3 ± 1

6.9 ± 1.7

6.8 ± 1.6

 

Pre-ablation Monocytes×109/L

   

0.0111

 Mean ± SD

0.6 ± 0.3

0.6 ± 0.3

0.6 ± 0.3

 

Pre-ablation Lymphocyte× 109/L

   

0.191

 Mean ± SD

1.5 ± 0.8

1.3 ± 0.7

1.4 ± 0.7

 

Post-ablation Lymphocyte× 109/L

   

0.831

 Mean ± SD

1.2 ± 0.7

1.2 ± 0.6

1.2 ± 0.6

 

Pre-ablation Neutrophils× 109/L

   

0.251

 Mean ± SD

3.4 ± 1.6

3.2 ± 1.7

3.3 ± 1.7

 

Post-ablation Neutrophils× 109/L

   

0.161

 Mean ± SD

4.5 ± 3.3

3.8 ± 2.8

4.1 ± 3

 

Pre-ablation NLR

   

0.871

 Mean ± SD

2.9 ± 1.8

2.9 ± 1.7

2.9 ± 1.7

 

Post-ablation NLR

   

0.821

 Mean ± SD

4.8 ± 6

4.4 ± 5.5

4.5 ± 5.7

 

Pre-ablation Platelets×109/L

   

0.331

 Mean ± SD

134.1 ± 75.4

123.3 ± 65

127.3 ± 69.1

 

Pre-ablation PLR

   

0.711

 Mean ± SD

104.5 ± 65.2

106.1 ± 56.8

105.5 ± 59.9

 

Pre-ablation LMR

   

0.691

 Mean ± SD

2.7 ± 1.6

2.7 ± 1.2

2.7 ± 1.4

 
  1. 1Kruskal Wallis test, 2Chi-Square test, AFP alpha fetoprotein, HDL high density lipoprotein, LDL low density lipoprotein, NLR neutrophil lymphocytes ratio, PLR platelets lymphocytes ratio, LMR lymphocytes monocytes ratio