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Table 2 Operating characteristics for the platform design with primary endpoint of disease control rate (DCR)

From: PIONEER-Panc: a platform trial for phase II randomized investigations of new and emerging therapies for localized pancreatic cancer

  Control Arm n = 30 for experimental arms
Experiment Arm 1 Experiment Arm 2 Experiment Arm 3 Experiment Arm 4
True DCR 0.70 0.70 0.80 0.90 0.95
Number of patients 42.6 30.0 30.0 30.0 30.0
Start Time (months) 0 0 6 12 18
Probability of claiming success 0.148 0.441 0.833 0.964