Table 4 Results from the Jonckheere Terpstra test evaluating the association between preoperative blood tests and tumor size, and perilobular and intralobular fibrosis, atrophy and chronic inflammation
No perilobular fibrosis, median (IQR) | Mild perilobular fibrosis, median (IQR) | Moderate perilobular fibrosis, median (IQR) | Severe perilobular fibrosis, median (IQR) | p | |
|---|---|---|---|---|---|
CRP (mg/l) | 5.0 (7.5) | 3.0 (7.5) | 5.0 (7.5) | 5.0 (7.5) | 0.480 |
High-sensitivity CRP (mg/l) | 5.8 (8.4) | 4.0 (8.4) | 3.7 (8.4) | 2.9 (8.4) | 0.246 |
Ca 19–9 (kU/l) | 129.0 (556.0) | 82.5 (556.0) | 176.5 (556.0) | 126.0 (556.0) | 0.454 |
CEA (μg/l) | 2.2 (2.7) | 2.5 (2.7) | 2.6 (2.7) | 3.0 (2.7) | 0.002 |
Albumin (g/l) | 37.4 (5.4) | 36.9 (5.4) | 37.3 (5.4) | 36.2 (5.4) | 0.027 |
Tumor size (mm) | 32.0 (15.0) | 30.0 (15.0) | 35.0 (15.0) | 30.0 (15.0) | 0.701 |
No intralobular fibrosis, median (IQR) | Mild intralobular fibrosis, median (IQR) | Moderate intralobular fibrosis, median (IQR) | Severe intralobular fibrosis, median (IQR) | p | |
CRP (mg/l) | 5.5 (7.5) | 3.0 (7.5) | 4.5 (7.5) | 5.0 (7.5) | 0.546 |
High-sensitivity CRP (mg/l) | 5.2 (8.4) | 4.1 (8.4) | 3.2 (8.4) | 3.1 (8.4) | 0.403 |
Ca 19–9 (kU/l) | 88.0 (556.0) | 147.0 (556.0) | 184.0 (556.0) | 158.5 (556.0) | 0.088 |
CEA (μg/l) | 2.0 (2.7) | 2.7 (2.7) | 2.8 (2.7) | 3.0 (2.7) | 0.002 |
Albumin (g/l) | 37.3 (5.4) | 36.4 (5.4) | 37.7 (5.4) | 36.2 (5.4) | 0.074 |
Tumor size (mm) | 30.0 (15.0) | 30.0 (15.0) | 35.0 (15.0) | 30.0 (15.0) | 0.556 |
No acinar atrophy, median (IQR) | Mild acinar atrophy, median (IQR) | Moderate acinar atrophy, median (IQR) | Severe acinar atrophy, median (IQR) | p | |
CRP (mg/l) | 5.0 (7.5) | 4.0 (7.5) | 4.0 (7.5) | 5.0 (7.5) | 0.431 |
High-sensitivity CRP (mg/l) | 4.9 (8.4) | 4.1 (8.4) | 3.4 (8.4) | 2.6 (8.4) | 0.268 |
Ca 19–9 (kU/l) | 124.0 (556.0) | 74.0 (556.0) | 168.0 (556.0) | 216.5 (556.0) | 0.058 |
CEA (μg/l) | 2.5 (2.7) | 2.5 (2.7) | 2.6 (2.7) | 3.1 (2.7) | 0.002 |
Albumin (g/l) | 37.2 (5.4) | 36.4 (5.4) | 37.6 (5.4) | 36.1 (5.4) | 0.009 |
Tumor size (mm) | 30.0 (15.0) | 30.0 (15.0) | 35.0 (15.0) | 30.0 (15.0) | 0.338 |
No chronic inflammation, median (IQR) | Mild chronic inflammation, median (IQR) | Moderate chronic inflammation, median (IQR) | Severe chronic inflammation, median (IQR) | p | |
CRP (mg/l) | 4.5 (7.5) | 4.0 (7.5) | 6.0 (7.5) | 4.0 (7.5) | 0.328 |
High-sensitivity CRP (mg/l) | 3.2 (8.4) | 3.1 (8.4) | 3.5 (8.4) | 2.8 (8.4) | 0.964 |
Ca 19–9 (kU/l) | 121.0 (556.0) | 173.0 (556.0) | 184.0 (556.0) | 322.0 (556.0) | 0.167 |
CEA (μg/l) | 2.5 (2.7) | 2.7 (2.7) | 3.4 (2.7) | 2.4 (2.7) | 0.004 |
Albumin (g/l) | 37.1 (5.4) | 37.0 (5.4) | 35.9 (5.4) | 34.9 (5.4) | 0.007 |
Tumor size (mm) | 30.0 (15.0) | 30.0 (15.0) | 33.0 (15.0) | 25.0 (15.0) | 0.231 |