Characteristic | Category | Univariate analysis HR (95%CI) | *P -Value | Multivariate analysis HR (95%CI) | P -Value |
---|---|---|---|---|---|
Age at diagnosis | ≤60 years | 1 | - | 1 | - |
61-70 years | 1.47 (0.90-2.42) | 0.118 | 0.86 (0.49-1.50) | 0.609 | |
71-80 years | 2.44 (1.57-3.95) | <0.001 | 1.26 (1.12-2.31) | 0.032* | |
≥81 years | 4.99 (2.98-8.36) | <0.001 | 2.33 (1.23-4.42) | 0.009* | |
Residence | Rural | 1 | - | 1 | - |
Urban | 0.74 (0.57.0.96) | 0.024 | 0.98 (0.74–1.23) | 0.067 | |
Marital status | Single | 1 | - | Not in model | - |
Married | 0.80 (0.51-1.25) | 0.331 | - | - | |
Occupation | Unemployed | 1 | - | 1 | - |
Worker | 0.80 (0.55-1.17) | 0.268 | 1.09 (0.71–1.68) | 0.683 | |
Self-employed | 0.74 (0.55-0.99) | 0.043 | 1.01 (0.74–1.38) | 0.967 | |
Employee | 0.28 (0.15-0.52) | <0.001 | 0.42 (0.20–0.87) | 0.021* | |
Education | Illiterate | 1 | - | 1 | - |
Diploma or below | 0.83 (0.71-0.93) | 0.042 | 0.91 (0.64–1.11) | 0.087 | |
Academic | 0.36 (0.19-0.68) | 0.002 | 0.78 (0.64–0.91) | 0.042* | |
Tobacco history | No | 1 | - | Not in model | - |
Yes | 0.99 (0.76-1.29) | 0.978 | - | - | |
Alcohol history | No | 1 | - | Not in model | Â |
Yes | 0.78 (0.35-1.77) | 0.568 | - | - | |
Family history of PC | No | 1 | Â | Not in model | - |
Yes | 1.13 (0.78-1.65) | 0.498 | - | - | |
Comorbidity | No | 1 | Â | 1 | - |
Yes | 1.28 (1.01-1.63) | 0.044 | 1.05 (0.85–1.14) | 0.124 | |
AJCC stage of disease | I | 1 | Â | 1 | Â |
II | 1.09 (0.74-1.62) | 0.634 | 1.03 (0.61-1.40) | 0.733 | |
III | 4.38 (3.09-6.20) | <0.001 | 1.45 (1.09-2.30) | 0.045* | |
IV | 8.55 (5.41-13.53) | <0.001 | 2.18 (1.09-3.68) | 0.025* | |
Gleason score | ≤ 6 | 1 |  | 1 | - |
7 | 2.19 (1.31-3.63) | 0.002 | 1.21 (0.69–1.40) | 0.501 | |
8 | 5.32 (2.34-8.97) | <0.001 | 4.16 (2.50–6.93) | 0.012* | |
≥ 9 | 8.14 (5.32-11.64) | <0.001 | 7.12 (5.35–10.28) | 0.002* | |
Treatment | No treatment | 1 | Â | 1 | - |
Active surveillance | 0.06 (0.03-0.11) | <0.001 | 0.14 (0.07-0.29) | 0.001* | |
Radical Prostatectomy | 0.07 (0.03-0.13) | <0.001 | 0.16 (0.08-0.37) | 0.001* | |
Radiotherapy | 0.25 (0.15-0.40) | <0.001 | 0.48 (0.28-0.83) | 0.008* | |
Radiotherapy + Radical Prostatectomy | 0.34 (0.20-0.57) | <0.001 | 0.42 (0.23-0.76) | 0.005* | |
Orchiectomy | 1 (0.64-1.56) | 0.977 | 0.48 (0.29-0.81) | 0.006* | |
Androgen therapy | 0.97 (0.85-1.20) | 0.185 | 0.68 (0.39-1.17) | 0.169 |