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Fig. 2 | BMC Cancer

Fig. 2

From: MiR-509-3p is oncogenic, targets the tumor suppressor PHLPP2, and functions as a novel tumor adjacent normal tissue based prognostic biomarker in colorectal cancer

Fig. 2

Upregulation of miR-509-3p induces cell proliferation and viability of CRC cells. Overexpression of miR-509-3p within stably transduced HCT116 and SW480 CRC cell lines resulted in an increase in their A proliferation rates – established using a BrdU assay, and B survival ability – established using a Clonogenic assay. E – relative to empty vector group, A – relative to (miR-509-3p (pre-mir) + Anti-miR-509-3p) group. *p value < 0.05; **p value < 0.01

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