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Table 6 Multivariable analysis using logistic regressions

From: Fatigue in breast cancer patients on chemotherapy: a cross-sectional study exploring clinical, biological, and genetic factors

Factor ORa 95% CI p-value
Model 1: Cycle number
 Cycle number 1.44 1.12–1.85 0.004
Model 2: Cycle number plus chemotherapy type and factors
 Cycle number 1.51 1.07–2.12 0.018
 Chemotherapy type    0.254
 Adjuvant vs Neoadjuvant 0.29 0.02–3.55 0.333
 Palliative vs Neoadjuvant 0.77 0.05–10.95 0.844
 Capecitabine 767 × 106 0 - Indefinite 1.000
 Cyclophosphamide 1.80 0.46–7.01 0.400
 Neuropathic pain treatment 1.18 0.08–18.03 0.904
Model 3: Biological measures
 Hemoglobin 0.67 0.45–0.99 0.046
 Leucocytes 1.00 1.00–1.00 0.189
 Platelets 1.00 1.00–1.00 0.733
Model 4: Genes
ABCB1 rs1045642 0.92 0.40–2.12 0.848
CLOCK rs1801260 TT vs TC 0.29 0.07–1.15 0.077
COMT rs4680 (V/V & V/M vs M/M) 1.37 0.29–6.38 0.693
PER2 rs934945 (GG & GA) vs AA 0.56 0.02–13.02 0.716
CRY2 rs10838524 (GG & GA) vs AA 3.12 0.44–21.89 0.253
DRD2 rs6277 (CC & CT vs TT) 4.09 1.02–16.48 0.047
Model 5: Full factor modela
 Cycle number 1.36 0.98–1.89 0.066
CLOCK rs1801260 TT vs TC 0.29 0.07–1.29 0.104
DRD2 rs6277 (CC & CT vs TT) 3.79 0.84–17.20 0.084
 Hemoglobin 0.38 0.50–1.30 0.376
  1. aFactors with p-value < 0.10 from other models were introduced