Table 4 Rank of the top 20 genes in the PPI network
From: A2M is a potential core gene in intrahepatic cholangiocarcinoma
Rank | Gene symbol | Gene description | Degree |
|---|---|---|---|
1 | CAT | Catalase | 28 |
2 | APOB | Apolipoprotein B | 24 |
2 | HP | Aaptoglobin | 24 |
2 | C3 | Complement component 3 | 24 |
5 | FGA | Fibrinogen alpha chain | 23 |
5 | AHSG | α2-HS-glycoprotein | 23 |
7 | APOE | Apolipoprotein E | 22 |
7 | KNG1 | Kininogen 1 | 22 |
7 | FGG | Fibrinogen gamma chain | 22 |
10 | GC | Group-specific component (vitamin D binding protein) | 21 |
11 | EHHADH | Enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase | 19 |
12 | TF | Transferrin | 18 |
13 | A2M | α2-macroglobulin | 17 |
13 | AMBP | Alpha-1-microglobulin | 17 |
13 | AGT | Angiotensinogen (serpin peptidase inhibitor, clade A, member 8) | 17 |
16 | HPX | Hemopexin | 16 |
17 | ITIH4 | Inter-alpha-trypsin inhibitor heavy chain family, member 4 | 15 |
17 | ACAA1 | Acetyl-CoA acyltransferase 1 | 15 |
19 | ACOX2 | Acyl-CoA oxidase 2, branched chain | 14 |
19 | ECI2 | Enoyl-CoA delta isomerase 2 | 14 |