Aberrant expression of CD54 detected by flow cytometry is a characteristic of B-lymphoma cells in bone marrow specimens

Table 2 Immunophenotype of thirteen patients diagnosed as BM involvement by using flow cytometry

Number	Lymphoma cells/nucleated cells in BM (%)	Subtype	Light-chain restriction	Aberrant antigen expression	CD54 MFIR
1	0.13	MCL	+	CD5	47.69
2	1.96	MCL	+	CD5	17.11
3	3.71	MCL	+	CD5	91.96
4	0.40	MCL	+	CD5	87.28
5	1.38	MCL	+	CD5	9.23
6	2.23	FL	+	CD10	11.30
7	1.25	FL	+	CD10	2.13
8	0.18	MZL	+	none	99.71
9	2	MZL	+	none	52.63
10	1.30	MZL	+	none	43.19
11	0.36	MZL	+	none	4.53
12	0.40	HG B-NHL	+	none	5.39
13	0.50	HG B-NHL	+^a	CD5	44.72

BM bone marrow, MFIR mean fluorescence index ratio, CLL/SLL Chronic lymphocytic leukemia/small lymphocytic lymphoma, MCL Mantle cell lymphoma, MZL Marginal zone lymphoma, FL Follicular lymphoma, LPL Lymphoplasmacytic lymphoma, HG B-NHL High-grade B-cell Non-Hodgkin lymphoma, BL Burkitt lymphoma
^aThis HG B-NHL lacked surface light-chain restriction, while had cytoplasmic light-chain restriction

ISSN: 1471-2407