Table 6 Univariate analysis and multivariate analysis for disease progression predictive factors of PDAC in TCGA

Age (≥ 66 vs. <  66)

0.943 (0.623-1.428)

0.782

–

–

Gender (Male vs. Female)

1.042 (0.690-1.573)

0.844

–

–

T stage (T3-T4 vs. T1-T2)

1.297 (0.668-2.519)

0.442

–

–

N stage (N2 vs. N1)

1.327 (0.814-2.163)

0.257

–

–

TNM Stage (II vs. I)

1.181 (0.513-2.723)

0.696

–

–

 (III vs. I)

1.169 (0.235-5.826)

0.848

–

–

 (IV vs. I)

1.077 (0.216-5.382)

0.927

–

–

Grade (G2 vs. G1)

0.799 (0.432-1.478)

0.474

0.690 (0.349-1.364)

0.286

 (G3 vs. G1)

1.253 (0.649-2.417)

0.501

1.182 (0.579-2.414)

0.646

 (G4 vs. G1)

7.490 (0.932-60.216)

0.058

4.819 (0.573-40.528)

0.148

Surgery type (Whipple and TP vs. DP and other type)

1.377 (0.784-2.418)

0.265

–

–

Residual tumour (R1-R2 vs R0)

2.309 (1.486-3.587)

< 0.001^*

2.590 (1.644-4.080)

< 0.001^*

History of diabetes (Yes vs. No)

0.715 (0.411-1.245)

0.236

–

–

SGLT-1 (SLC5A1) (High vs. Low)

0.547 (0.350-0.855)

0.008^*

0.534(0.336-0.848)

0.007^*

MAP-17 (PDZK1IP1) (High vs. Low)

1.018 (0.663-1.563)

0.934