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Fig. 4 | BMC Cancer

Fig. 4

From: Oral administration of cystine and theanine attenuates 5-fluorouracil-induced intestinal mucositis and diarrhea by suppressing both glutathione level decrease and ROS production in the small intestine of mucositis mouse model

Fig. 4

Protection against 5-FU-induced small intestinal GSH decrease by CT administration. a Small intestinal GSH level, b small intestinal GSSG level, and c small intestinal GSH/GSSG ratio are shown. Normal Control, control group receiving saline. 5-FU, receiving 5-FU (150 mg/kg) and methyl cellulose (the vehicle for CT). 5-FU + CT, receiving 5-FU (150 mg/kg) and CT (280 mg/kg). Values are expressed as the mean ± SEM. N = 5–6. *p < 0.05 vs normal control, **p < 0.01 vs normal control, ***p < 0.001 vs normal control by Tukey’s multiple comparisons test

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BMC Cancer

ISSN: 1471-2407

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