Table 2 Univariate analysis of risks of OS

Age

1.012 (1.006–1.018)

<0.001

Male

1.044 (0.932–1.170)

0.453

ALB

0.991 (0.981–1.002)

0.106

FBG

0.998 (0.992–1.004)

0.59

logCA199

1.318 (1.236–1.406)

<0.001

TB

1.000 (1.000–1.001)

0.164

Biliary drainage

1.057 (0.929–1.203)

0.398

Body/tail

1.085 (0.971–1.212)

0.149

Diagnostic year

0.103

 2013

Ref.

 2014

1.029 (0.762–1.389)

0.852

 2015

1.204 (0.910–1.594)

0.194

 2016

0.937 (0.715–1.228)

0.637

 2017

1.120 (0.858–1.460)

0.405

 2018

1.153 (0.880–1.512)

0.301

 2019

0.960 (0.707–1.304)

0.795

ASA Score

0.798

 1

Ref.

 2

0.977 (0.867–1.102)

0.709

 3

0.926 (0.748–1.148)

0.485

 4

1.180 (0.707–1.968)

0.527

Stage

<0.001

 Ia

Ref.

 Ib

1.168 (1.508–1.946)

0.002

 IIa

1.618 (1.186–2.207)

0.002

 IIb

2.197 (1.717–2.811)

<0.001

 III

3.213 (2.512–4.110)

<0.001

 IV

6.307 (4.831–8.235)

<0.001

Differentiation

<0.001

 I

Ref.

 II

2.645 (0.372–18.835)

0.331

 III

3.941 (0.554–28.008)

0.171

 IV

41.974 (2.616–673.418)

0.008

 Unknown

1.399 (0.127–15.446)

0.784

Chemotherapy

0.511 (0.458–0.570)

<0.001

Surgical intervention

0.254 (0.207–0.309)

<0.001

BMI

0.964 (0.946–0.983)

<0.001

X-Tile categorizing

<0.001

  < 18.9

Ref.

 18.9–23.3

0.745 (0.626–0.886)

0.001

  ≥ 23.3

0.665 (0.556–0.794)

<0.001

WHO categorizing

<0.001

  < 18.5

Ref.

 18.5–23

0.625 (0.514–0.759)

<0.001

  ≥ 23

0.563 (0.462–0.685)

<0.001