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Table 2 Anterior pituitary dysfunction after cranial irradiation for skull base meningioma

From: High prevalence of anterior pituitary deficiencies after cranial radiation therapy for skull base meningiomas

 

Follow-up (years)

Hormonal axis dysfunction n (%)

3

5

10

At least one of the 5 axes

10/52 (19.2%)

16/39 (31.5%)

22/26 (60.2%)

Corticotroph

7/52 (13.5%)

8/37 (15.4%)

8/17 (15.4%)

Somatotroph

3/52 (5.8%)

5/35 (9.8%)

6/16 (13.4%)

Gonadotroph

5/52 (9.6%)

9/37 (17.8%)

13/20 (36.9%)

Thyrotroph

3/52 (5.8%)

7/35 (14%)

10/18 (28%)

Lactotroph

1/52 (1.9%)

5/35 (10.1%)

7/17 (18.5%)