Table 3 Univariate and multivariate analysis for overall survival of gastric cancer patients using Cox proportional hazard model and a stepwise procedure

Age (≥ 70 vs. <  70)

<  0.0001

4.968

3.206–7.700

<  0.0001

3.915

2.515–6.093

Gender (male vs. female)

0.1855

1.392

0.853–2.273

Tumor size (≥ 4 cm vs. < 4 cm)

<  0.0001

2.604

1.751–3.861

Histology (undifferentiated vs. differentiated)

0.4867

1.105

0.776–1.703

Depth of invasion (T2/T3/T4 vs. T1)

<  0.0001

2.599

1.750–3.858

Lymph node metastasis (present vs. absent)

<  0.0001

3.096

2.090–4.584

0.0042

1.923

1.229–3.010

Lymphatic invasion (present vs. absent)

<  0.0001

2.487

1.573–3.934

Vascular invasion (present vs. absent)

<  0.0001

3.332

2.163–5.134

0.0114

1.898

1.155–3.119

Approach (open vs. laparoscopy)

<  0.0001

3.140

1.857–5.309

0.0238

1.888

1.088–3.275

Gatrectomy (total vs. distal and proximal partial)

0.0002

2.237

1.471–3.401

Lymph node dissection (D2 vs. D0/D1)

0.0166

1.623

1.092–2.410

Adjuvant chamotherapy (present vs. absent)

0.0034

1.939

1.245–3.018

Preoperative PDW (PDW^High vs. PDW^Low)

0.0020

1.900

1.266–2.853

0.0009

2.031

1.338–3.082

Preoperative RDW (RDW^High vs. RDW^Low)

<  0.0001

2.882

1.946–4.268

< 0.0001

2.553

1.714–3.802