Fig. 4

TEX41 directly sponges miR-103a-3p in melanoma cells. A-B The localization of TEX41 in melanoma cells was determined by FISH and Nucleo-cytoplasmic separation assays. C The enrichment of candidate miRNAs in Bio-TEX41 was assessed by RNA pull down assay. D The interaction between TEX41 and miR-103a-3p was confirmed by Ago2-RIP assay. E The binding sites between TEX41 and miR-103a-3p were predicted by starBase. F-G RNA pull down and luciferase reporter assays were performed to confirm the predicted binding sites between TEX41 and miR-103a-3p. * P < 0.05, ** P < 0.01