Table 8 Quantile regression analysis results of Eratio and the expression levels of TGF- β 1, Smad2/3, Erk1/2, p38 MAPK, JNK2, PI3K and AKT
Factors | Percentiles | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
0.05 | 0.15 | 0.25 | 0.35 | 0.45 | 0.55 | 0.65 | 0.75 | 0.85 | 0.95 | |
Constant | − 0.058 (− 0.079) | −0.586 (− 0.946) | 0.045 (0.077) | 0.087 (0.182) | 0.319 (0.687) | 0.695 (0.980) | 0.226 (0.284) | 0.080 (0.136) | −0.119 (− 0.035) | 4.236 (0.441) |
TGF-β1 | 13.933 (4.601**) | 6.751 (2.509*) | 11.378 (4.419**) | 14.082 (6.820**) | 15.654 (7.768**) | 14.928 (4.840**) | 15.123 (4.366**) | 18.126 (7.125**) | 19.985 (7.339**) | 110.466 (7.731**) |
Erk1/2 | 2.771 (0.608) | 6.286 (1.648) | 0.249 (0.068) | −0.499 (−0.170) | −3.591 (−1.257) | − 3.766 (− 0.861) | −3.841 (− 0.782) | −0.037 (− 0.01) | 0.913 (0.043) | −39.144 (− 0.662) |
Smad2/3 | −6.359 (− 1.417) | − 5.757 (− 1.533) | −4.420 (− 1.230) | −3.594 (− 1.247) | −6.242 (− 2.219*) | −6.249 (− 1.451) | − 2.435 (− 0.504) | −4.113 (− 1.158) | − 5.014 (− 0.241) | 44.481 (0.764) |
AKT | 5.978 (1.500) | 3.844 (1.152) | 1.196 (0.375) | 0.376 (0.147) | 2.971 (1.189) | 3.361 (0.878) | 3.160 (0.736) | 2.215 (0.702) | 3.831 (0.207) | −15.238 (− 0.295) |
PI3K | − 1.496 (− 0.378) | − 0.647 (− 1.196) | 2.862 (0.904) | 3.808 (1.500) | 3.338 (1.234) | 3.905 (1.209) | 5.633 (1.322) | 5.043 (1.612) | 4.127 (0.225) | −13.009 (− 0.254) |
P38 MAPK | − 2.112 (− 0.630) | 0.385 (0.137) | −1.337 (− 0.498) | −1.521 (− 0.706) | − 2.104 (− 1.001) | − 0.774 (− 0.241) | −2.010 (− 0.557) | −0.933 (− 0.352) | −2.056 (− 0.132) | 5.076 (0.117) |
JNK2 | 5.940 (1503) | 2.384 (0.721) | 1.748 (0.552) | 0.377 (0.149) | 1.763 (0.712) | 2.336 (0.616) | 4.779 (1.122) | 3.031 (0.969) | 5.463 (0.298) | 26.230 (0.511) |