Factors | Percentiles | |||||||||
---|---|---|---|---|---|---|---|---|---|---|
0.05 | 0.15 | 0.25 | 0.35 | 0.45 | 0.55 | 0.65 | 0.75 | 0.85 | 0.95 | |
Constant | 0.527 (0.474) | −0.714 (− 0.311) | 0.367 (0.156) | − 0.120 (− 0.049) | − 2.526 (− 0.757) | −2.043 (− 0.624) | −1.405 (− 0.423) | −2.446 (− 0.703) | −2.194 (− 0.503) | −2.805 (− 0.042) |
TGF-β1 | 22.480 (4.946**) | 70.439 (7.503**) | 63.092 (6.578**) | 75.920 (7.501**) | 109.328 (8.017**) | 113.801 (8.509**) | 112.599 (8.286**) | 104.303 (7.337**) | 132.677 (7.440**) | 117.040 (2.217*) |
Erk1/2 | 12.786 (1.758) | −12.731 (− 0.891) | −9.527 (− 0.653) | −10.331 (− 0.671) | −2.835 (− 0.137) | − 10.140 (− 0.498) | −6.910 (− 0.334) | −4.137 (− 0.191) | 5.001 (0.184) | 18.186 (0.407) |
Smad2/3 | −10.225 (− 1.492) | − 25.332 (− 1.886) | −4.195 (− 0.306) | 0.339 (0.023) | 1.619 (0.083) | 7.046 (0.368) | 19.713 (1.014) | 31.167 (1.532) | 12.837 (0.503) | 81.503 (1.912) |
AKT | 11.152 (1.653) | −3.635 (− 0.322) | 2.482 (0.215) | 1.541 (0.127) | −3.895 (− 0.237) | −7.848 (− 0.488) | − 11.279 (− 0.690) | 13.315 (0.779) | 2.485 (0.116) | −2.034 (− 0.37) |
PI3K | −6.335 (− 1.163) | 6.578 (0.585) | − 0.590 (− 0.051) | 3.185 (0.263) | 10.962 (0.671) | 17.097 (1.067) | 16.826 (1.033) | 19.973 (1.172) | 14.122 (0.661) | 13.965 (0.319) |
P38 MAPK | 5.410 (1.138) | 13.940 (1.374) | 10.201 (0.984) | 11.205 (1.024) | 10.597 (0.719) | 11.347 (0.785) | 12.809 (0.872) | 1.537 (0.100) | −18.073 (− 0.938) | −49.386 (− 1.073) |
JNK2 | − 11.226 (1.490) | 7.915 (0.673) | 5.724 (0.477) | −2.051 (− 0.162) | − 12.575 (− 0.736) | −15.636 (− 0.934) | −24.628 (− 1.447) | −18.915 (− 1.062) | 9.965 (0.446) | 22.565 (0.472) |