Table 6 Quantile regression analysis results of Emean and the expression levels of TGF- β 1, Smad2/3, Erk1/2, p38 MAPK, JNK2, PI3K and AKT
Factors | Percentiles | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
0.05 | 0.15 | 0.25 | 0.35 | 0.45 | 0.55 | 0.65 | 0.75 | 0.85 | 0.95 | |
Constant | 2.515 (2.764**) | 5.153 (0.614) | 5.302 (0.607) | 3.906 (0.535) | 5.219 (0.937) | 7.044 (1.129) | 8.812 (1.174) | 12.887 (1.893) | 19.159 (2.447*) | 52.857 (3.331**) |
TGF-β1 | 165.740 (40.847**) | 272.166 (7.273**) | 275.848 (7.078**) | 306.187 (9.404**) | 311.012 (12.523**) | 330.379 (11.878**) | 331.917 (9.913**) | 348.870 (11.493**) | 396.475 (11.353**) | 283.164 (4.001**) |
Erk1/2 | 9.134 (1.869) | 27.242 (0.518) | 5.337 (0.097) | −19.645 (− 0.429) | −14.899 (− 0.427) | −26.436 (− 0.676) | − 62.152 (− 1.320) | −89.939 (− 2.107*) | −70.397 (− 1.434) | − 137.854 (− 1.385) |
Smad2/3 | −10.401 (− 1.948) | − 29.460 (− 0.590) | 28.310 (0.523) | 59.515 (1.316) | 48.011 (1.391) | 74.255 (1.921) | 34.924 (0.900) | 149.744 (3.550**) | 87.728 (1.808) | 167.575 (1.738) |
AKT | 6.943 (1.198) | 58.972 (1.271) | −13.985 (− 0.289) | − 40.210 (− 0.996) | 4.966 (0.161) | 13.972 (0.405) | −5.790 (− 1.139) | − 41.723 (− 1.108) | − 20.310 (− 0.469) | −117.021 (− 1.333) |
PI3K | − 9.712 (− 1.911) | − 15.839 (− 0.344) | − 26.241 (− 0.548) | 2.051 (0.051) | −16.296 (− 0.534) | −22.552 (− 0.659) | −35.817 (− 0.870) | − 50.265 (− 1.347) | −63.175 (− 1.471) | − 176.770 (− 1.761) |
P38 MAPK | −8.844 (− 1.818) | − 2.021 (− 0.052) | 10.735 (0.264) | − 18.712 (− 0.551) | −6.704 (− 0.259) | −6.008 (− 0.207) | 9.940 (0.285) | 43.607 (1.378) | 85.537 (2.349) | 191.916 (1.836) |
JNK2 | 9.514 (1.901) | −30.758 (− 0.676) | − 15.982 (− 0.337) | 1.976 (0.050) | − 9.354 (− 0.310) | −22.872 (− 0.676) | 8.012 (0.197) | 33.942 (0.920) | −13.712 (− 0.323) | 28.135 (0.327) |