Fig. 2

Alterations of the PD-L1/PD-L2 locus were investigated by FISH using a PD-L1/PD-L2 probe (labeled with Spectrum Red) and a CEP 9 probe (labeled with Spectrum Green). Representative FISH images revealed amplification of the PD-L1/PD-L2 locus in Patient 1, indicated by a red signal (white arrow)