Skip to main content

Table 1 Clinicopathological characteristics of the epithelial component of carcinosarcoma and the status of intratumoral stromal CD3, CD4, CD8, FOXP3, PD-1, PD-L1 and PD-L2 (N = 57)

From: The prevalence and prognostic impact of tumor-infiltrating lymphocytes in uterine carcinosarcoma

Clinicopathological features Total no. of cases CD3_E CD4_E CD8_E FOXP3_E PD-1_E PD-L1_E PD-L2_E
Low High p-value Low High p-value Low High p-value Low High p-value Low High p-value Low High p-value Low High p-value
Age N = 57
 <  60 17 6 11 0.838 2 15 0.052 3 14 0.513 11 6 0.523 7 10 0.138 5 12 0.022 1 16 0.413
 ≥ 60 40 13 27 15 25 12 28 30 10 25 15 25 15 7 33
Stage N = 57
 I/II 15 2 13 0.038 2 13 0.025 5 10 0.584 10 5 0.697 6 9 0.138 8 7 0.587 0 15 0.041
 III/IV 42 17 25 15 27 10 32 31 11 26 16 22 20 8 34
Histological subtype N = 42
 Heterologous 30 9 21 0.292 12 18 0.277 8 22 0.715 23 7 0.699 18 12 0.740 21 9 0.158 5 25 0.298
 Homologous 12 6 6 2 10 4 8 8 4 8 4   5 7   0 12  
LVI N = 41
 Present 25 4 12 1.000 3 13 0.712 7 9 0.053 12 4 0.734 13 12 0.790 13 12 0.606 4 21 1.000
 Absent 16 6 19 7 18 3 22 17 8 9 7 7 9 2 14
  1. Differences in absolute value correspond to missing data. Significant P-values are emboldened
  2. LVI Lymphovascular Invasion, E Epithelial Component, ER Estrogen Receptor, PR Progesterone Receptor, CD3 Cluster of Differentiation 3, CD4 Cluster of Differentiation 4, CD8 Cluster of Differentiation 8, FOXP3 Forkhead Box P3, PD-1 Programmed Cell Death Protein 1, PD-L1 Programmed Death-Ligand 1, PD-L2 Programmed Death-Ligand 2