From: METTL14 gene polymorphisms decrease Wilms tumor susceptibility in Chinese children
Haplotypes a | Cases (n = 806) | Controls (n = 2396) | Crude OR (95% CI) | P | Adjusted OR b (95% CI) | Pb |
---|---|---|---|---|---|---|
TGAAC | 78 (9.68) | 233 (9.72) | 1.00 | Â | 1.00 | Â |
TGAAT | 41 (5.09) | 111 (4.63) | 0.88 (0.57–1.34) | 0.542 | 0.87 (0.57–1.33) | 0.516 |
TGAGC | 209 (25.93) | 550 (22.95) | 0.90 (0.68–1.20) | 0.468 | 0.90 (0.68–1.19) | 0.464 |
TGAGT | 242 (30.02) | 744 (31.05) | 0.77 (0.59–1.02) | 0.064 | 0.77 (0.59–1.02) | 0.066 |
TGGAT | 4 (0.50) | 0 (0.00) | / | / | / | / |
TGGGC | 5 (0.62) | 1 (0.04) | 11.85 (1.37–102.72) | 0.025 | 11.15 (1.28–96.76) | 0.029 |
TGGGT | 3 (0.37) | 1 (0.04) | 7.11 (0.73–69.18) | 0.091 | 7.50 (0.77–73.05) | 0.083 |
TAAAT | 1 (0.12) | 0 (0.00) | / | / | / | / |
TAAGC | 1 (0.12) | 0 (0.00) | / | / | / | / |
AGGAT | 23 (2.85) | 79 (3.30) | 0.69 (0.41–1.16) | 0.162 | 0.70 (0.41–1.16) | 0.172 |
AGGGC | 65 (8.06) | 193 (8.06) | 0.80 (0.55–1.15) | 0.227 | 0.80 (0.55–1.15) | 0.221 |
AGGGT | 23 (2.85) | 69 (2.88) | 0.79 (0.47–1.34) | 0.380 | 0.80 (0.47–1.36) | 0.417 |
AGAAC | 3 (0.37) | 0 (0.00) | / | / | / | / |
AGAAT | 2 (0.25) | 1 (0.04) | 4.74 (0.43–52.87) | 0.206 | 5.23 (0.47–58.94) | 0.180 |
AGAGC | 1 (0.12) | 1 (0.04) | 2.37 (0.15–38.27) | 0.543 | 2.46 (0.15–39.70) | 0.527 |
AGAGT | 9 (1.12) | 55 (2.30) | 0.39 (0.19–0.82) | 0.012 | 0.40 (0.19–0.84) | 0.016 |
AAGAC | 1 (0.12) | 0 (0.00) | / | / | / | / |
AAGGC | 2 (0.25) | 2 (0.08) | 2.37 (0.33–17.06) | 0.392 | 2.32 (0.32–16.75) | 0.403 |
AAGGT | 9 (1.12) | 58 (2.42) | 0.37 (0.18–0.77) | 0.008 | 0.38 (0.18–0.80) | 0.010 |
AAAAC | 0 (0.00) | 2 (0.08) | / | / | / | / |
AAAAT | 18 (2.23) | 70 (2.92) | 0.61 (0.35–1.08) | 0.088 | 0.62 (0.35–1.09) | 0.096 |
AAAGC | 34 (4.22) | 162 (6.76) | 0.50 (0.32–0.77) | 0.002 | 0.50 (0.32–0.77) | 0.002 |
AAAGT | 32 (3.97) | 64 (2.67) | 1.19 (0.73–1.92) | 0.492 | 1.19 (0.73–1.93) | 0.488 |