Table 3 Univariate and multivariate cox regression analyses for overall survival in cervical cancer patients in primary cohort

  ≤ 45 years vs. > 45 years

0.99 (0.64–1.55)

0.984

Histological grade

0.228

 G1

Ref.

–

 G2

1.01 (0.43–2.81)

0.486

 G3

1.60 (0.63–4.05)

0.325

  > 1/2 vs. ≤1/2

1.79 (1.11–2.87)

0.017^*

0.99 (0.57–1.71)

0.970

  > 4 vs. ≤4

2.10 (1.33–3.30)

0.001^*

1.25 (0.75–2.08)

0.397

 Yes vs. No

2.11 (1.30–3.43)

0.003^*

2.27 (1.38–3.73)

0.001^*

FIGO stage

< 0.001^*

< 0.001^*

 IA

Ref.

Ref.

 IB

3.37 (1.44–7.89)

0.005^*

3.85 (1.60–9.29)

0.003^*

 IIA

8.18 (3.37–19.86)

< 0.001^*

10.16 (3.69–27.98)

< 0.001^*

Yes vs. No

0.70 (0.35–1.40)

0.312

  > 0.41 vs. ≤0.41

0.42 (0.26–0.67)

< 0.001^*

0.32 (0.19–0.51)

< 0.001^*

  > 2.75 vs. ≤2.75

1.62 (1.04–2.54)

0.034^*

1.53 (0.97–2.43)

0.070

  > 128 vs. ≤128

1.96 (1.22–3.15)

0.006^*

1.57 (0.92–2.68)

0.096

  > 0.27 vs. ≤0.27

1.83 (1.18–2.85)

0.007^*

1.50 (0.90–2.51)

0.122