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Table 1 Clinicopathological characteristics in the LNM- (n = 289) and LNM+ groups (n = 65)

From: The risk of lymph node metastasis in gastric cancer conforming to indications of endoscopic resection and pylorus-preserving gastrectomy: a single-center retrospective study

Factor

LNM- (n = 289)

LNM+ (n = 65)

LNM%

Relative risk (CI 95%)

P-value

Age (years)

56.74 ± 11.084

54.80 ± 12.677

  

0.301

  < 40

16

10

38.46%

2.297 (1.333–3.947)

0.006

  ≥ 40

273

55

16.77%

  

Sex

    

0.373

 Male

186

38

16.96%

  

 Female

103

27

20.77%

  

BMI (kg/m2)

21.08 ± 5.914

21.24 ± 5.782

  

0.874

Size (cm)

 Length-diameter

2.091 ± 1.198

2.930 ± 1.689

  

0.009

 Short-diameter

1.713 ± 1.126

2.196 ± 1.342

  

0.068

   < 2 cm

152

26

14.61%

1.712 (0.924–3.174)

0.076

   ≥ 2 cm

137

39

22.16%

  

   < 3 cm

236

39

14.18%

2.496 (1.532–4.065)

< 0.001

   ≥ 3 cm

53

26

32.91%

  

Tumor marker

 CEA (U/mL)

7.032 ± 81.39

4.394 ± 9.618

  

0.631

 CA125 (U/mL)

10.31 ± 9.527

9.995 ± 5.774

  

0.566

 CA199 (U/mL)

13.689 ± 59.54

17.703 ± 45.017

  

0.526

Location

 Upper

27

6

18.18%

 

0.765

 Middle

136

28

17.07%

  

 Lower

142

31

17.92%

  

Depth of invasion

 Tis

41

1

2.38%

 

< 0.001

 T1a

152

25

14.12%

  

 T1b

98

37

27.41%

  

Differentiation

 Well/Moderate

155

14

8.28%

 

< 0.001

 Poorly

134

51

27.57%

3.328 (1.914–5.787)

 

Ulcer finding

 Absent

133

36

21.30%

 

0.172

 Present

156

29

15.68%

  

Number of lymph nodes

36.97 ± 24.157

40.63 ± 18.23

  

0.864

LVI

 Absent

283

55

16.27%

 

< 0.001

 Present

6

10

62.5%

3.751 (2.422–5.809)

 

Recurrence

7

2

   

OS ratea

94.54%

80.77%

  

0.021

DFS ratea

93.64%

79.17%

  

0.011

  1. BMI body mass index, LNM lymph node metastasis, LVI lymphovascular invasion, LNM- absence of lymph node metastasis, LNM+ presence of lymph node metastasis, CI confidence interval, CEA carcinoembryonic antigen, CA125 cancer antigen 125, CA199 cancer antigen 199, OS overall survival, DFS disease-free survival
  2. aThe 5-year survival rate refers to the survival status of patients treated with surgery between January 2010 and March 2015. The OS rates were as follows: LNM-, 104/107 (94.54%); LNM+, 20/24 (80.77%). The DFS rates were as follows: LNM-, 103/107 (96.26%); LNM+, 19/24 (79.17%)