Table 3 Health-Related Quality of Life at 1 year follow-up including curative intent oesophageal and GOJ cancer patients
|  | cT0-T1 | cT2–4 Surgery | cT2–4 dCRT | cT0-T1 compared to cT2–4 Surgery adjusted | cT0-T1 compared to cT2–4 dCRT adjusted | cT2–4 Surgery compared to cT2–4 dCRT adjusted |
|---|---|---|---|---|---|---|
QLQ-C30 | Mean (CI) n (145) | Mean (CI) n (539) | Mean (CI) n (92) | MD (CI) | MD (CI) | MD (CI) |
Global health/QOL | 64 (60 to 69) | 61 (59 to 63) | 58 (53 to 64) | −4 (−9 to 1) | − 6 (−13 to 2) | − 2 (−8 to 4) |
Functions | ||||||
 Physical function | 79 (76 to 82) | 76 (74 to 78) | 72 (67 to 77) | −3 (−8 to 1) | −6 (−12 to 0) | −4 (−9 to 1) |
 Role function | 71 (66 to 76) | 66 (63 to 69) | 65 (59 to 71) | −5 (−11 to 2) | − 5 (− 14 to 4) | −1 (−9 to 7) |
 Emotional function | 76 (72 to 80) | 76 (75 to 79) | 75 (70 to 79) | 0 (− 5 to 5) | −3 (− 10 to 3) | −2 (− 7 to 3) |
 Cognitive function | 83 (79 to 86) | 83 (81 to 85) | 79 (74 to 84) | 0 (−4 to 4) | −5 (−11 to 1) | − 4 (− 9 to 0) |
 Social function | 76 (71 to 80) | 72 (70 to 74) | 70 (64 to 76) | −4 (−9 to 2) | − 7 (− 14 to 1) | −3 (− 9 to 4) |
Symptoms | ||||||
 Fatigue | 35 (31 to 40) | 41 (39 to 44) | 45 (39 to 50) | 6 (1 to 12) | 9 (1 to 16) | 3 (−3 to 9) |
 Nausea and vomiting | 11 (8 to 15) | 18 (16 to 20) | 13 (9 to 18) | 5 (0 to 9) | 0 (−6 to 5) | −5 (−10 to 0) |
 Pain | 27 (22 to 31) | 25 (22 to 27) | 25 (19 to 30) | −3 (−8 to 3) | −2 (−9 to 5) | 2 (− 4 to 8) |
 Dyspnoea | 31 (27 to 36) | 35 (32 to 38) | 36 (30 to 42) | 5 (−1 to 11) | 6 (−2 to 14) | 1 (−6 to 8) |
 Insomnia | 24 (19 to 29) | 29 (27 to 32) | 23 (17 to 28) | 3 (−3 to 9) | −2 (− 10 to 6) | −6 (− 13 to 1) |
 Loss of appetite | 20 (15 to 25) | 29 (26 to 32) | 30 (22 to 37) | 10 (3 to 16) | 7 (−2 to 16) | 0 (−8 to 8) |
 Constipation | 12 (8 to 16) | 11 (9 to 13) | 14 (9 to 19) | −2 (−6 to 3) | 1 (− 6 to 8) | 3 (− 2 to 8) |
 Diarrhoea | 21 (16 to 26) | 26 (23 to 28) | 11 (7 to 15) | 3 (−3 to 8) | −10 (− 17 to − 3) | −14 (− 20 to − 8) |
 Financial | 11 (7 to 16) | 15 (13 to 17) | 14 (8 to 19) | 1 (−4 to 6) | 2 (−5 to 9) | 1 (− 5 to 7) |
QLQ-OG25 | ||||||
 Function | ||||||
  Body Image | 79 (74 to 84) | 73 (70 to 76) | 70 (63 to 78) | −7 (−13 to 0) | −9 (− 18 to 0) | −1 (− 9 to 7) |
 Symptoms | ||||||
  Dysphagia | 18 (13 to 23) | 22 (19 to 24) | 34 (27 to 42) | 5 (−1 to 11) | 16 (8 to 25) | 11 (4 to 18) |
  Eating | 24 (20 to 28) | 34 (32 to 36) | 34 (28 to 40) | 10 (5 to 15) | 8 (1 to 16) | −1 (−7 to 5) |
  Reflux | 23 (18 to 28) | 25 (23 to 28) | 20 (14 to 25) | 2 (−3 to 8) | −4 (−12 to 3) | −8 (− 14 to − 1) |
  Odynophagia | 18 (13 to 22) | 18 (16 to 20) | 23 (18 to 29) | −1 (−6 to 4) | 3 (−4 to 10) | 5 (0 to 11) |
  Pain and discomfort | 26 (22 to 31) | 27 (25 to 29) | 23 (17 to 28) | 0 (−5 to 5) | −5 (−12 to 3) | −4 (− 10 to 2) |
  Anxiety | 40 (35 to 44) | 44 (42 to 47) | 47 (39 to 54) | 4 (−2 to 10) | 7 (−1 to 16) | 3 (−4 to 10) |
  Eating with others | 15 (10 to 20) | 18 (16 to 21) | 23 (17 to 29) | 4 (−1 to 10) | 9 (1 to 17) | 4 (−3 to 11) |
  Dry mouth | 27 (22 to 32) | 28 (26 to 32) | 28 (21 to 35) | 3 (−3 to 9) | 2 (−6 to 11) | −1 (−9 to 6) |
  Trouble with taste | 18 (13 to 22) | 22 (19 to 25) | 28 (21 to 35) | 4 (−2 to 10) | 9 (1 to 18) | 6 (−1 to 13) |
  Trouble swallowingsaliva | 8 (5 to 11) | 12 (10 to 14) | 14 (9 to 19) | 3 (−2 to 7) | 5 (−1 to 11) | 2 (−4 to 7) |
  Choked when swallowing | 14 (11 to 18) | 16 (14 to 18) | 27 (20 to 35) | 3 (−2 to 8) | 13 (5 to 20) | 10 (4 to 16) |
  Trouble with coughing | 28 (23 to 32) | 31 (29 to 34) | 32 (25 to 39) | 3 (−3 to 9) | 1 (−7 to 10) | 0 (−7 to 7) |
  Trouble talking | 9 (6 to 13) | 11 (9 to 13) | 19 (12 to 25) | 5 (0 to 9) | 13 (6 to 20) | 5 (−1 to 10) |
  Weight loss | 19 (14 to 24) | 34 (31 to 37) | 27 (20 to 34) | 18 (11 to 25) | 9 (1 to 17) | −8 (−16 to 0) |
  Hair loss | 23 (12 to 36) | 21 (17 to 26) | 23 (11 to 36) | −5 (−18 to 9) | −9 (−28 to 10) | −3 (− 15 to 10) |