Fig. 3

PART1 targets miR-503-5p. A The predicted complementary binding site of PART1 and miR-503-5p. B The luciferase activity in OC cells co-transfected with pGL3-PART1 WT/pGL3-PART1 MUT and miR-503-5p/miR-NC was determined by dual luciferase reporter assay. ***P < 0.001 vs. the miR-NC group. C The expression of miR-503-5p in OC tissues (n = 50) and normal tissues (n = 50) was detected by qRT-PCR. ***P < 0.001 vs. the normal group. D The correlation between the expression PART1 and miR-503-5p in OC tissues was assessed by Pearson’s correlation analysis. P < 0.001, R² = 0.665. E The expression of miR-503-5p after transfection of sh-PART1–2/NC into OC cells was detected by qRT-PCR. ***P < 0.001 vs. the sh-NC group