Table 2 Immunotherapy Treatment

Settings

< 0.001

 Clinical trial

161 (38.9)

102 (32.3)

59 (60.2)

 Compassionate program

31 (7.5)

26 (8.2)

5 (5.1)

 Clinical practice

222 (53.6)

188 (59.5)

34 (34.7)

Treatment setting

0.074

 Adjuvant

6 (1.4)

5 (1.6)

1 (1.0)

 1st line metastasis

214 (51.7)

152 (48.1)

62 (63.3)

 2nd line metastasis

113 (27.3)

92 (29.1)

21 (21.4)

  ≥ 3rd line metastasis

81 (19.6)

67 (21.2)

14 (14.3)

Immunotherapy combination

0.004

 Single agent

322 (77.8)

250 (79.1)

72 (73.5)

 Combination ICI + ICI

19 (4.6)

8 (2.5)

11 (11.2)

 Combination ICI + chemotherapy

62 (15.0)

50 (15.8)

12 (12.2)

 Combination ICI + others

11 (2.7)

8 (2.5)

3 (3.1)