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Table 1 Clinical data in malignant and nonmalignant IPMNs

From: The association between serum ferritin levels and malignant intraductal papillary mucinous neoplasms

 

Total

(n = 151)

Malignant IPMNs

(n = 47)

Nonmalignant IPMNs

(n = 104)

p

Age

63.28 ± 9.47

63.59 ± 8.99

62.60 ± 10.50

0.55

Size

3.69 ± 1.98

3.93 ± 1.63

3.58 ± 2.11

0.34

Sex (male/female)

84/47

29/11

55/36

0.28

Dysplasia

  Low-intermediate grade

104

/

104

 

  High-grade

24

24

0

 

  Invasion

23

13

0

 

Type

   

<  0.01

  Main

24

16

8

 

  Branch

73

9

64

 

  Mixed

54

22

32

 

Location

   

0.15

  Head-neck

95

34

61

 

  Body and Tail

56

13

43

 

CEA (ng/ml)

3.57 ± 3.61

4.75 ± 5.65

3.03 ± 1.95

0.09

  CEA > 5.0

24

10

14

0.22

CA19–9 (U/ml)

48.68 ± 228.65

99.04 ± 396.08

26.19 ± 70.67

0.002

  > 37

29

17

12

<  0.001

Ferritin (ng/ml)

275.03 ± 284.65

370.58 ± 358.19

231.84 ± 233.76

0.001

  > 232

60

26

34

0.009

MPD diameter

0.61 ± 0.41

0.90 ± 0.49

0.48 ± 0.29

<  0.001

Chronic cholecystitis

56

17

39

0.87

Pancreatitis

3

0

3

0.24

Abdominal Symptoms

67

23

44

0.92

Diabetes

23

9

14

0.13

Lymph node metastasis (yes vs no)

2

2

0

0.09

Peripancreatic extension

5

5

0

0.003

Mural nodule

17

13

4

<  0.01

  1. Malignant IPMNs were defined as those with high grade dysplasia and associated invasive carcinoma
  2. CA 19–9 carbohydrate antigen 19–9; CEA carcinoembryonic antigen; MPD main pancreatic duct