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Fig. 1 | BMC Cancer

Fig. 1

From: Identification of TRPV4 as a novel target in invasiveness of colorectal cancer

Fig. 1

Inhibition of TRPV4 suppresses colon cancer cell migration and invasion. A and B representative images and summary data of the migration assay in HCT-116 cells and SW620 cells transfected with siCTL, siTRPV4#1 and siTRPV4#2 or treated with Vehicle or HC-067047, scale bar: 50 μm. C and D representative images and summary data of the wound healing assay in HCT-116 cells and SW620 cells transfected with siCTL, siTRPV4#1 and siTRPV4#2 or treated with Vehicle or HC-067047. E and F Representative images and summary data from invasion assay in HCT-116 cells and SW620 cells transfected with siCTL, siTRPV4#1 and siTRPV4#2 or treated with Vehicle or HC-067047, scale bar: 50 μm. Values represent the mean ± SEM, #, p < 0.05 compared to siCTL or Vehicle

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