Parameters | Univariate analysis | Multivariate analysis | ||
---|---|---|---|---|
HR (95% CI) | P | HR (95% CI) | P | |
Age (>60 vs ≤60) | 1.282 (0.745–2.204) | 0.370 | ||
Sex (male vs female) | 0.927 (0.552–1.555) | 0.773 | ||
B symptoms (present vs absent) | 1.421 (0.815–2.480) | 0.216 | ||
LDH (>ULN vs normal) | 2.260 (1.329–3.843) | 0.003 | ||
ECOG score (2-4 vs 0-1) | 2.111 (1.228–3.630) | 0.007 | ||
Ann Arbor Stage (III-IV vs I-II) | 2.253 (1.214–4.179) | 0.010 | ||
Extranodal disease (>1 vs ≤1) | 2.063 (1.226–3.472) | 0.006 | ||
IPI | <0.001 | <0.001 | ||
Low risk (0-1) | reference | reference | ||
Low-intermediate risk (2) | 1.592 (0.726–3.490) | 0.245 | 1.592 (0.726–3.490) | 0.245 |
High-intermediate risk (3) | 4.238 (2.127–8.444) | <0.001 | 4.238 (2.127–8.444) | <0.001 |
High risk (4-5) | 3.140 (1.406–7.012) | 0.005 | 3.140 (1.406–7.012) | 0.005 |
Subtype (GCB vs non-GCB) | 1.151 (0.774–1.711) | 0.487 | ||
FFAs (high vs normal) | 2.050 (1.193–3.525) | 0.009 |