Table 1 Clinicopathologic characteristics of study population

 Median (IQR)

53.1 (43.6–61.6)

49.1 (40.6–59.1)

0.095

 Mean ± SD

23.5 ± 4.0

24.2 ± 3.5

0.204

Surgical approach

0.002

 Open

74 (54.0)

49 (80.3)

 Laparoscopy

53 (38.7)

9 (14.8)

 Robot-assisted surgery

10 (7.3)

3 (4.9)

Conization

22 (16.1)

12 (19.7)

0.534

Histologic type

0.858

 Squamous cell carcinoma

112 (81.8)

48 (78.7)

 Adenocarcinoma

20 (14.6)

10 (16.4)

 Adenosquamous carcinoma

5 (3.6)

3 (4.9)

2009 FIGO stage

0.254

 IB1

70 (51.1)

29 (47.5)

 IB2

32 (23.4)

12 (19.7)

 IIA1

13 (9.5)

12 (19.7)

 IIA2

22 (16.1)

8 (13.1)

Pelvic lymphadenectomy

N/A

 No

0

0

 Yes

137 (100.0)

61 (100.0)

  Removed LNs, median (IQR)

23 (16–31)

29 (21–35)

0.001

  Positive LNs, median (IQR)

0 (0–2)

1 (0–4)

< 0.001

Para-aortic lymphadenectomy

0.050

 No

100 (73.0)

36 (59.0)

 Yes

37 (27.0)

25 (41.0)

  Removed LNs, median (IQR)

3 (2–5.5)

4 (2.5–6)

0.235^a

  Positive LNs, median (IQR)

0 (0–0)

0 (0–1)

0.004^a

 Mean ± SD

34.8 ± 13.9

31.9 ± 13.9

0.163

 Median (IQR)

41.0 (30.5–56.0)

40.0 (30.0–51.5)

0.378

  < 20

6 (4.4)

5 (8.2)

0.504

  ≥ 20 and < 40

56 (40.9)

23 (37.7)

  ≥ 40 and < 50

26 (19.0)

15 (24.6)

  ≥ 50

49 (35.8)

18 (29.5)

 Parametrial invasion

46 (33.6)

25 (41.0)

0.316

 LN metastasis

63 (46.0)

44 (72.1)

0.001

  Pelvic LN only

62 (45.3)

37 (60.7)

0.008^b

  Both pelvic and para-aortic LNs

1 (0.7)

7 (11.5)

  Para-aortic LN only

0

0

 Resection margin involvement

15 (10.9)

9 (14.8)

0.449

 LVSI

109 (79.6)

47 (77.0)

0.690

 Deep stromal invasion

115 (83.9)

46 (75.4)

0.155

Indication for CCRT

0.002

 High-risk factor

87 (63.5)

52 (85.2)

 Intermediate-risk factors

50 (36.5)

9 (14.8)