Category | One FDR affected by BCa-1 | One FDR affected by BCa-2 |
|---|
N a | RR b | 95%CI | N a | RR b | 95%CI |
|---|
Overall | 5345 | 1.68 | 1.63–1.73 | 298 | 1.68 | 1.49–1.88 |
Age at diagnosis of BC in FDR |
≤ 50 years old | 967 | 1.89 | 1.78–2.02 | 11 | 1.72 | 0.95–3.10 |
> 50 years old | 4378 | 1.63 | 1.58–1.68 | 287 | 1.67 | 1.49–1.88 |
Type of the affected FDR |
Only mother | 3716 | 1.70 | 1.64–1.76 | 224 | 1.69 | 1.48–1.93 |
Only sister | 1597 | 1.61 | 1.53–1.69 | 68 | 1.59 | 1.25–2.83 |
Only brother or father | 32 | 1.77 | 1.25–2.51 | 6 | 2.19 | 0.98–4.87 |
- aN, number of BC cases diagnosed during the follow-up in women
- bRR was estimated from Poisson regression using individuals without cancer family history as the reference. The covariates adjusted in the model included age groups (5 years), periods (5 years), parity (number of live birth: 0, 1, 2, 3, over 3), socioeconomic status (blue-collar worker, white-collar worker, farmer, private business, professional, or other/unspecified) and place of residence (big cities, northern Sweden, southern Sweden and unspecific). Significant RRs are in bold
- BC breast cancer, BCa-1 breast cancer as a first primary malignancy, BCa-2 breast cancer as a second primary malignancy, FDR first-degree relative, RR relative risk, 95%CI 95% confidence interval
