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Table 3 Performance evaluation of the radiomic models using SVM algorithm in the training and validation cohort

From: Predicting response to immunotherapy plus chemotherapy in patients with esophageal squamous cell carcinoma using non-invasive Radiomic biomarkers

 

Models

Accuracy

Sensitivity

Specificity

NPV

PPV

AUC

Training cohort

3D uncorrected

0.701

0.590

0.814

0.720

0.734

0.626

(0.690–0.718)

(0.570–0.622)

(0.796–0.831)

(0.700–0.735)

(0.702–0.754)

(0.602–0.637)

3D corrected

0.690

0.581

0.814

0.705

0.752

0.628

(0.680–0.702)

(0.556–0.607)

(0.792–0.834)

(0.694–0.721)

(0.720–0.776)

(0.583–0.611)

2D uncorrected

0.801

0.693

0.900

0.779

0.915

0.776

(0.800–0.821)

(0.681–0.715)

(0.886–0.932)

(0.771–0.799)

(0.910–0.932)

(0.772–0.791)

2D corrected

0.804

0.727

0.886

0.795

0.917

0.818

(0.793–0.815)

(0.706–0.742)

(0.855–0.900)

(0.784–0.803)

(0.896–0.925)

(0.797–0.829)

Validation cohort

3D uncorrected

0.640

0.431

0.864

0.602

0.750

0.531

(0.632–0.666)

(0.36–0.49)

(0.813–0.900)

(0.575–0.631)

(0.694–0.811)

(0.502–0.560)

3D corrected

0.640

0.432

0.861

0.601

0.750

0.514

(0.631–0.660)

(0.363–0.491)

(0.800–0.911)

(0.570–0.632)

(0.691–0.811)

(0.480–0.544)

2D uncorrected

0.790

0.709

0.860

0.710

0.852

0.729

(0.770–0.801)

(0.681–0.756)

(0.830–0.891)

(0.564–1.000)

(0.830–0.881)

(0.711–0.760)

2D corrected

0.796

0.714

0.872

0.753

0.848

0.787

(0.770–0.806)

(0.673–0.767)

(0.841–0.901)

(0.721–0.786)

(0.813–0.875)

(0.752–0.806)

  1. Abbreviations: SVM-Support Vector Machine, AUC-Area under the Receiver-Operating Characteristic Curve, NPV-Negative Predictive Value, PPV-Positive Predictive Value